Acro Disc PSF Syringe Filters w/ PVDF Membrane - 0.45um, 25mm, 200/Pk
Pall SKU: AP-4408

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 200/Pk - AP-4408

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. The hydrophilic PVDF membrane keeps analyte adsorption low for clean recovery and resists HPLC mobile phases, alcohols, and mild hydrocarbons. Polypropylene construction resists chemical degradation from routine sample matrices and maintains a low-dead-volume internal flow path. Where small-volume samples must reach the instrument clean, syringe filtration clears particulates in a single pass.

Technical Specifications

• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Absolute pore size rating gives consistent results across protocols
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Thin membrane structure sustains high flow for fast sample throughput
• Mechanically durable membrane holds integrity under filtration pressure

Housing Specifications

• Tough polypropylene body tolerates repeated handling at the bench
• Thermal-bonded construction keeps adhesives out of the fluid path
• Stable across the full aqueous pH range in routine sample work
• Optimized internal geometry minimizes backpressure in service

Filtering particulates upstream protects the column investment your methods depend on. Reliable particulate removal protects your instruments and your data so column life and baseline stability stay predictable. Start a live chat with our customer support technicians for quick answers to your compatibility, sizing, and sterility questions.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation