Acro Disc PSF Syringe Filters w/ Supor Membrane - GxF/0.45um, 25mm, 200/Pk
Pall SKU: AP-4425

Pall Acrodisc Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 200/Pk - AP-4425

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. Syringe filters mount on a syringe to clarify a sample in a single manual pass. Naturally hydrophilic PES wets on contact with aqueous samples while keeping protein adsorption low across the run and stays stable across the pH 1 to 14 range. The PP housing sustains efficient flow on viscous samples while contributing minimal extractables to the filtrate and holds a reliable seal against the membrane edge. Where small-volume samples must reach the instrument clean, syringe filtration clears particulates in a single pass.

Technical Specifications

• Absolute pore size rating gives consistent results across protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Broad compatibility with aqueous buffers, aliphatic alcohols, glycols, and strong bases
• High flow rate with low extractable background for clean preparations
• Low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Resists aqueous acids, bases, and alcohols in routine sample prep
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Medical-grade polypropylene with broad chemical compatibility
• Thermal-bonded construction keeps adhesives out of the fluid path

Upstream clarification pays for itself by keeping your columns clear and your analytical day on schedule. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Connect with our customer support technicians for chemical compatibility guidance and the right filtration product for your workflow.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Burst Pressure (psi)

75psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

300ml

Holdup Volume

< 100 µL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophilic

• Biologicals - Maximizes recovery of high-value proteins and therapeutics during sterile filtration steps, protecting yield in production runs
• Time-Sensitive Prep - Accelerates filtration workflows where speed is critical to preserving sample integrity and preventing biological degradation
• High-Throughput Sterile Filtration - Processes large volumes of biological fluids significantly faster than standard PES to reduce processing time
• Viscous Biologicals - Maintains flow rates even when filtering protein-rich or slightly viscous biological fluids that would clog other filters
• Buffer Filtration - Ensures particulate-free buffers for critical downstream processes and instrumentation to prevent costly system downtime
• Media Preparation - Sterilizes tissue culture media with minimal protein loss, ensuring optimal cell growth and viability in sensitive cultures