Acro Disc PSF Syringe Filters w/ Supor Membrane - GxF/0.45um, 25mm, 1000/Pk
Pall SKU: AP-4426

Pall Acrodisc Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - AP-4426

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. PES delivers sharp particle cutoff at the rated pore size while drawing aqueous samples through without pre-wetting and handles strong bases across a broad aqueous range. The PP housing keeps the fluid path low in extractable contamination while staying inert across common laboratory solvents and holds a reliable seal against the membrane edge. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• High flow rate with low extractable background for clean preparations
• Stable across the full pH 1 to 14 operating range
• Broad compatibility with aqueous buffers, aliphatic alcohols, glycols, and strong bases
• Low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Resists aqueous acids, bases, and alcohols in routine sample prep
• Medical-grade polypropylene with broad chemical compatibility
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Reliable housing-to-membrane seal prevents bypass at rated pressure

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. General-purpose aqueous filtration supports the sample types you handle every day so you can standardize one filter across most aqueous methods. Reach out to the Tisch Scientific team for application support, volume pricing, and technical assistance with your filtration product selection.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Burst Pressure (psi)

75psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

300ml

Holdup Volume

< 100 µL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophilic

• Buffer Filtration - Ensures particulate-free buffers for critical downstream processes and instrumentation to prevent costly system downtime
• Time-Sensitive Prep - Accelerates filtration workflows where speed is critical to preserving sample integrity and preventing biological degradation
• Viscous Biologicals - Maintains flow rates even when filtering protein-rich or slightly viscous biological fluids that would clog other filters
• Media Preparation - Sterilizes tissue culture media with minimal protein loss, ensuring optimal cell growth and viability in sensitive cultures
• High-Throughput Sterile Filtration - Processes large volumes of biological fluids significantly faster than standard PES to reduce processing time
• Biologicals - Maximizes recovery of high-value proteins and therapeutics during sterile filtration steps, protecting yield in production runs