Acro Disc PSF Syringe Filters w/ Nylon Membrane - 0.45um, 25mm, 200/Pk
Pall SKU: AP-4438

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 200/Pk - AP-4438

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. Sample preparation for chromatography often ends with a syringe filter on the path to the vial. Nylon wets on contact with aqueous samples through its hydrophilic surface and clarifies particulates at the rated pore size. The PP housing keeps the fluid path low in extractable contamination while resisting degradation from routine sample matrices and maintains housing integrity through the filtration run. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Stable across the pH 3 to 12 operating range
• Alkaline-resistant across a broad range of aqueous buffers
• Non-sterile for routine clarification and sample prep
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• High tensile strength for stability under elevated differential pressures

Housing Specifications

• Medical-grade polypropylene with broad chemical compatibility
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Stable across the full aqueous pH range in routine sample work

Removing particulates from your buffers and mobile phases extends column life and keeps your baselines steady. Reliable particulate removal protects your instruments and your data so column life and baseline stability stay predictable. Call on the Tisch Scientific team to standardize filtration products across your methods with volume pricing and documentation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing