ACRO Disc PSF w/ 0.45um Nylon 50/Pk
Pall SKU: AP-4438TC

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 50/Pk - AP-4438TC

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. Syringe filters give the analyst a single-use device for clarifying samples right at the bench. Nylon withstands elevated differential pressures with high tensile strength while fitting routine analytical sample preparation and resists alkaline buffer systems. The PP housing prevents sample bypass under rated operating pressure while keeping the fluid path low in extractable contamination and resists degradation from routine sample matrices. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Absolute pore size rating provides consistent results across filtration protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Alkaline-resistant across a broad range of aqueous buffers
• Non-sterile for routine clarification and sample prep
• Low extractable contribution to sensitive analytical preparations

Housing Specifications

• Stable across the full aqueous pH range in routine sample work
• Optimized internal geometry minimizes backpressure in service
• Thermal-bonded construction keeps adhesives out of the fluid path
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate

Reproducible separations start with samples that reach the column free of particulates. Pre-injection filtration protects the resolution your methods depend on by clearing particulates ahead of the column and frits. Request a quality certificate, lot documentation, or a blanket-order quote from the Tisch Scientific support team.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Connection Type

Luer-Lock/ Luer Slip

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

215ml

Holdup Volume

< 125 µL

Material

Nylon

Maximum Operating Pressure

60psi

Maximum Operating Temperature (°C)

82°C

Pack Count

50

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Buffer Filtration - Delivers high mechanical strength for efficient clarification of alkaline buffers and aqueous reagents in the lab.
• Solvent Filtering - Supports clarification of ester-based and alcohol solvents with precision during routine laboratory sample processing.
• Mobile Phase Prep - Clarifies aqueous and organic HPLC mobile phases to protect columns and stabilize chromatographic baselines downstream.
• Chemical Analysis - Withstands aggressive bases and alcohols, ideal for tough chemical compatibility filtration challenges in routine analysis.
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from aqueous mobile phases in HPLC.
• Dissolution Testing - Supports accurate drug release profiles by clarifying dissolution samples ahead of HPLC quantitation in QC labs.