Acro Disc PSF Syringe Filters w/ PVDF Membrane - 0.45um, 25mm, 1000/Pk
Pall SKU: AP-4500

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - AP-4500

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. The PVDF membrane clarifies samples at the rated pore size and keeps analyte adsorption low for clean recovery. The polypropylene housing routes flow to minimize backpressure in service and resists aqueous acids, bases, and alcohols. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Thin membrane structure sustains high flow for fast sample throughput
• Absolute pore size rating gives consistent results across protocols
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons

Housing Specifications

• Plasticizer-free polyolefin construction keeps the fluid path clean
• Stable across the full aqueous pH range in routine sample work
• Low extractable contribution protects sensitive downstream analyses
• Optimized internal geometry minimizes backpressure in service

Filtering particulates upstream protects the column investment your methods depend on. Upstream buffer clarification keeps avoidable particulates out of your flow path while keeping the filtrate analytically clean. Connect with our customer support technicians for chemical compatibility guidance and the right filtration product for your workflow.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily