Acro Disc PSF Syringe Filters w/ Nylon Membrane - 0.2um, 25mm, 1000/Pk
Pall SKU: AP-4522

Pall Acrodisc Nylon Syringe Filters, 0.2 µm, 25 mm, 1000/Pk - AP-4522

Pall's engineering and quality infrastructure extends from its process-scale filtration systems to its laboratory devices. Under hand pressure from the syringe, the membrane captures particulates as the sample passes through. The nylon membrane resists alkaline conditions across a broad buffer range and draws aqueous buffers through without pre-wetting. The PP housing keeps the fluid path low in extractable contamination and stays inert across common laboratory solvents. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Absolute pore size rating provides consistent results across filtration protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• High tensile strength for stability under elevated differential pressures
• Stable across the pH 3 to 12 operating range
• Broad compatibility with alcohols, aliphatic, and aromatic solvents

Housing Specifications

• Plasticizer-free polyolefin construction keeps the fluid path clean
• Rigid polypropylene body holds its shape under manual filtration pressure
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Low extractable contribution protects sensitive downstream analyses

Reproducible separations start with samples that reach the column free of particulates. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Request a quality certificate, lot documentation, or a blanket-order quote from the Tisch Scientific support team.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

42psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

75ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging