Acro Disc PSF Syringe Filters w/ Nylon Membrane - GxF/0.45um, 25mm, 1000/Pk
Pall SKU: AP-4528

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - AP-4528

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. The nylon matrix handles alcohols and aliphatic and aromatic solvents and resists particle shedding through extended cycles. The polypropylene housing routes flow to minimize backpressure in service while holding extractables low for sensitive analyses and maintains housing integrity through the filtration run. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Absolute pore size rating provides consistent results across filtration protocols
• Non-sterile for routine clarification and sample prep
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Low extractable contribution protects sensitive downstream analyses
• Thermal-bonded construction keeps adhesives out of the fluid path
• Medical-grade polypropylene with broad chemical compatibility

Sample clarification before injection is the cheapest insurance your chromatography system has. Pre-injection filtration protects the resolution your methods depend on by clearing particulates ahead of the column and frits. Call on the Tisch Scientific team to standardize filtration products across your methods with volume pricing and documentation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases