Pall
Acro Disc PSF Syringe Filters w/ Nylon Membrane - GxF/0.45um, Autopack Tubes (25/Pkg 200/cs) SKU: AP-4548

Nylon (NY) Syringe Filters, 0.45µm, 25mm - AP-4548

Designed to protect sensitive chromatography columns from clogging, the Nylon Syringe Filters delivers exceptional retention of particulates without compromising flow rates. Driving this clarification performance is a hydrophilic Nylon membrane featuring a verified 0.45 pore structure that captures target particulates while minimizing holdup volume. Complementing the membrane's purity, the housing's thermal bonding eliminates the need for adhesives, removing a common source of extractable contamination. Ultimately, this rigorous attention to manufacturing quality ensures batch-to-batch reproducibility, allowing laboratories to standardize their workflows with total confidence.

Key Nylon Membrane Characteristics

• Nylon membrane with hydrophilic affinity
• High Protein Binding characteristics
• Excellent resistance to esters, bases, and alcohols
• Avoid with strong acids (pH < 3) or protein samples (high binding)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 125 µl holdup volume to minimize sample loss

By selecting a filter that matches the exact chemical nature of your samples, you ensure that your workflow remains uninterrupted by membrane failures. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

215ml

Holdup Volume

< 125 µL

Material

Nylon

Maximum Operating Pressure

60psi

Maximum Operating Temperature (°C)

55°C

Pack Count

25

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Borosilicate Glass (GxF)

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wetability

Hydrophilic

• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging