Acro Disc PSF Syringe Filters w/ Nylon Membrane - GxF/0.45um, 200/Pk
Pall SKU: AP-4549

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 200/Pk - AP-4549

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. Nylon includes a built-in prefilter that sustains flow on high-particulate samples while delivering sharp particle cutoff at the rated pore size and supports high-volume routine filtration. The PP housing prevents sample bypass under rated operating pressure while resisting degradation from routine sample matrices and sustains efficient flow on viscous samples. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Non-sterile for routine clarification and sample prep
• Layered prefiltration sustains flow through turbid, particulate-laden samples
• Low extractable contribution to sensitive analytical preparations
• Alkaline-resistant across a broad range of aqueous buffers
• Absolute pore size rating provides consistent results across filtration protocols

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Thermal-bonded construction keeps adhesives out of the fluid path
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Stable across the full aqueous pH range in routine sample work

Reproducible separations start with samples that reach the column free of particulates. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Connect with our customer support technicians for chemical compatibility guidance and the right filtration product for your workflow.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

215ml

Holdup Volume

< 125 µL

Material

Nylon

Maximum Operating Pressure

60psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis