Acro Disc PSF Syringe Filters w/ Nylon Membrane - GxF/0.45um, 50/Pk
Pall SKU: AP-4549TC

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm - AP-4549TC

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. Across analytical workflows, the syringe filter is where particulates leave the sample stream. The nylon matrix handles alcohols and aliphatic and aromatic solvents while supporting high-volume routine filtration and accepts water-based samples without surfactant conditioning. The PP housing prevents sample bypass under rated operating pressure while holding extractables low for sensitive analyses and maintains a low-dead-volume internal flow path. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Low extractable contribution to sensitive analytical preparations
• Stable across the pH 3 to 12 operating range
• Alkaline-resistant across a broad range of aqueous buffers
• High tensile strength for stability under elevated differential pressures

Housing Specifications

• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Thermal-bonded construction keeps adhesives out of the fluid path
• Tough polypropylene body tolerates repeated handling at the bench

Reproducible separations start with samples that reach the column free of particulates. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Contact Tisch Scientific for technical guidance on selecting the right filtration product for your specific application requirements.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Construction

Polypropylene (PP)

Diameter

25mm

Material

Nylon

Pore Size (µm)

0.45

Sterility

Nonsterile

Wettability

Hydrophilic

• Environmental Testing - Provides robust filtration for water quality samples, removing sediments prior to critical analytical testing steps.
• Chemical Analysis - Withstands aggressive bases and alcohols, ideal for tough chemical compatibility filtration challenges in routine analysis.
• Buffer Filtration - Delivers high mechanical strength for efficient clarification of alkaline buffers and aqueous reagents in the lab.
• Dissolution Testing - Supports accurate drug release profiles by clarifying dissolution samples ahead of HPLC quantitation in QC labs.
• Solvent Filtering - Supports clarification of ester-based and alcohol solvents with precision during routine laboratory sample processing.
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from aqueous mobile phases in HPLC.