Pall
Acro Disc One Syringe Filters w/ wwPTFE Membrane - 0.45um, 25mm, 200/Pk SKU: AP-4916

Hydrophilic PTFE (wwPTFE) Syringe Filters, 0.45µm, 25mm - AP-4916

The Acrodisc® One with wwPTFE (Water-Wettable PTFE) membrane dissolves the traditional distinction between aqueous and organic filtration workflows. To dissolve the barrier between aqueous and organic workflows, the hydrophilic PTFE structure wets immediately without the need for alcohol flushing. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. Meeting the needs of regulated environments, this series supports compliance with stringent purity protocols across pharmaceutical and environmental applications.

Key Hydrophilic PTFE (wwPTFE) Membrane Characteristics

• Hydrophilic PTFE (wwPTFE) membrane with hydrophilic (water-wettable) affinity
• Low Protein Binding characteristics
• Universal compatibility (Aqueous + Organic)
• None; compatible with virtually all lab solvents
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

Your laboratory throughput depends on reliable consumables, and these filters are designed to keep your sequences running smoothly, sample after sample. You invest significant resources into your samples; safeguarding them with a proven filtration barrier is a cost-effective insurance policy for your lab. When performance cannot be compromised, rely on the brand that has defined the science of filtration for decades.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

26psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

240ml

Holdup Volume

< 100 µL

Material

Hydrophilic PTFE (wwPTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophilic

• Dissolution Testing - Simplifies workflows by filtering diverse media types without the need for pre-wetting, streamlining high-volume protocols
• Sample Protection - Low-binding properties ensure maximum recovery of low-concentration analytes to improve the accuracy of quantitative assays
• Universal Filtration - Handles both aqueous and organic samples with a single device, reducing inventory complexity and preventing selection errors
• Solvent Selection - Eliminates the risk of membrane incompatibility when switching between different solvent systems during method development
• UHPLC/HPLC Prep - Certified for low extractables to ensure noise-free baselines in sensitive chromatography applications and trace analysis
• Ion Chromatography - Provides a clean filtrate for sensitive ion analysis, minimizing background interference and ensuring accurate quantification