Pall
Acro Disc One Syringe Filters w/ wwPTFE Membrane - GxF/0.45um, 25mm, 1000/Pk SKU: AP-4921

Hydrophilic PTFE (wwPTFE) Syringe Filters, 0.45µm, 25mm - AP-4921

Streamline your HPLC and dissolution testing with a single filtration solution: the Hydrophilic PTFE (wwPTFE) Syringe Filters with water-wettable PTFE technology. Central to this universality is the wwPTFE membrane, which remains chemically compatible with aggressive solvents while being fully water-wettable. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. Consequently, by reducing the risk of downstream contamination, these filters serve as a critical safeguard for the integrity of your experimental results.

Key Hydrophilic PTFE (wwPTFE) Membrane Characteristics

• Hydrophilic PTFE (wwPTFE) membrane with hydrophilic (water-wettable) affinity
• Low Protein Binding characteristics
• Universal compatibility (Aqueous + Organic)
• None; compatible with virtually all lab solvents
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. Trust in the consistent performance of your filtration step to remove the variables that often lead to costly re-runs and ambiguous data. Choose Pall technology to ensure that your critical samples are processed with the highest level of recovery and sterility available.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

26psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

240ml

Holdup Volume

< 100 µL

Material

Hydrophilic PTFE (wwPTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophilic

• Sample Protection - Low-binding properties ensure maximum recovery of low-concentration analytes to improve the accuracy of quantitative assays
• Solvent Selection - Eliminates the risk of membrane incompatibility when switching between different solvent systems during method development
• Ion Chromatography - Provides a clean filtrate for sensitive ion analysis, minimizing background interference and ensuring accurate quantification
• Dissolution Testing - Simplifies workflows by filtering diverse media types without the need for pre-wetting, streamlining high-volume protocols
• UHPLC/HPLC Prep - Certified for low extractables to ensure noise-free baselines in sensitive chromatography applications and trace analysis
• Universal Filtration - Handles both aqueous and organic samples with a single device, reducing inventory complexity and preventing selection errors