Acro Disc One Syringe Filters w/ wwPTFE Membrane - GxF/0.45um, 25mm, 1000/Pk
Pall SKU: AP-4921

Pall Acrodisc Water-Wettable PTFE Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - AP-4921

Pall's engineering and quality infrastructure extends from its process-scale filtration systems to its laboratory devices. Syringe filters mount on a syringe to clarify a sample in a single manual pass. The hydrophilic PTFE membrane clarifies particulates at the rated pore size while accepting aqueous samples without pre-wetting and preserves dilute proteins in the filtrate. The PP housing stays inert across common laboratory solvents and buffers in routine use while routing flow to minimize backpressure in service and holds extractables low for sensitive analyses. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Absolute pore-size rating gives consistent retention across protocols
• Chemically inert to aggressive organic solvents, strong acids, and alkalis
• Universal compatibility across aqueous buffers and organic solvents
• Low protein binding preserves dilute analytes for maximum recovery
• Water-wettable surface wets directly with both aqueous and organic samples

Housing Specifications

• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Medical-grade polypropylene with broad chemical compatibility
• Stable across the full aqueous pH range in routine sample work

Upstream clarification pays for itself by keeping your columns clear and your analytical day on schedule. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Send your application details to our technical service team and request a filtration product recommendation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

26psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

240ml

Holdup Volume

< 100 µL

Material

Hydrophilic PTFE (wwPTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophilic

• Sample Protection - Low-binding properties ensure maximum recovery of low-concentration analytes to improve the accuracy of quantitative assays
• Solvent Selection - Eliminates the risk of membrane incompatibility when switching between different solvent systems during method development
• Ion Chromatography - Provides a clean filtrate for sensitive ion analysis, minimizing background interference and ensuring accurate quantification
• Dissolution Testing - Simplifies workflows by filtering diverse media types without the need for pre-wetting, streamlining high-volume protocols
• UHPLC/HPLC Prep - Certified for low extractables to ensure noise-free baselines in sensitive chromatography applications and trace analysis
• Universal Filtration - Handles both aqueous and organic samples with a single device, reducing inventory complexity and preventing selection errors