VacuCap 0.2um, 60mm, Gamma-Irradiated , 10/Pk SKU: TA4632

Polyethersulfone (PES) Capsule Filters - TA4632

When bench-scale filtration volumes exceed syringe filter capacity but do not require in-line capsule systems, VacuCap devices bridge the gap with vacuum-driven convenience. Built for consistent results, bottle-top capsule construction seats the membrane assembly directly above the collection vessel, creating a sealed vacuum-driven fluid path that eliminates the tubing and fittings required by in-line capsule formats. In turn, the result is a filtration workflow that scales efficiently from method development through production, delivering consistent retention performance across the full range of capsule effective filtration areas.

Key Polyethersulfone (PES) Membrane Characteristics

• The non-sterile capsule format offers a cost-effective option for applications where particle removal rather than sterility assurance is the primary filtration objective.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.
• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• Internal holdup volume of 2.2 milliliters minimizes sample loss during capsule filtration, a critical consideration when processing expensive biologics or limited-volume preparations.

Key Capsule Construction Features

• Sealed acrylic capsule construction is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device ships.
• Modified acrylic housing delivers low extractable levels suitable for aqueous biological and pharmaceutical filtration applications where fluid purity is a primary concern.
• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.
• Bottle-top vacuum filtration design seats directly on standard laboratory collection vessels, creating a sealed fluid path from feed tubing through the membrane to the receiving container.

Whether your process requires sterilizing-grade retention for a 500-milliliter bench trial or clarification capacity for a 100-liter production batch, the right capsule filter configuration eliminates the compromises between throughput, retention, and operational simplicity. For exactly this reason, if your laboratory prepares culture media, buffers, or reagents at bench scale, VacuCap bottle-top filtration delivers membrane-grade retention with the vacuum-driven simplicity your daily workflow demands. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Housing material limitations preclude autoclave sterilization, making the device appropriate for non-sterile applications including particulate removal, sample clarification, and general-purpose laboratory filtration.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Capsule Format

VacuCap

Compliance Standards

Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Diameter

6 cm

Filling Bell (Yes/ No)

No

Filtration Area

30 cm²

Flow Rate

0.2 L/min at 10 in. Hg

Holdup Volume

2.2 mL

Inlet Connection

Feed tubing port

Material

PES

Max Batch Volume

1 L

Maximum Operating Pressure

25 in. Hg (vacuum)

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Vacuum port (bottle-top seal)

Pack Count

10

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Not suitable for sterile applications

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
• Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
• Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.
• Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.
• Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.
• Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.