Sterile-Grade PES Capsule Filter, 0.20um, 60mm x 115mm, 3/8 in. Hose Barb, Gamma Sterile, 1/Pk SKU: SPEC21202

Polyethersulfone (PES) Capsule Filters - SPEC21202

Ultra-low protein binding and broad pH compatibility from 1 to 14 make PES capsule filters the preferred membrane choice for processing biological solutions at production scale. Engineered for demanding applications, the pleated PES membrane pack maximizes effective filtration area within the capsule housing, sustaining high flow rates through large batch volumes while inherent hydrophilicity ensures immediate wetting without alcohol pre-treatment. The outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.

Key Polyethersulfone (PES) Membrane Characteristics

PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
The 75.4 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.
PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
Single-membrane capsule design provides a straightforward retention barrier for applications where feed quality is controlled and extended dirt-holding capacity is not the primary requirement.
The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.

Key Capsule Construction Features

Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. To address this, if your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Sealed sterile packaging preserves validated sterility throughout storage and transport, providing a documented sterile barrier that is ready for use at the point of need.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.