Polyethersulfone (PES) Capsule Filters - SF15017
PES capsule filters combine asymmetric membrane architecture with ultra-low protein adsorption, maximizing throughput while preserving the biological activity of filtered solutions. Asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. Taken together, the result is a streamlined filtration step that integrates directly into fluid transfer systems, reducing hold times and minimizing the manual handling that compromises sterility assurance.
Key Polyethersulfone (PES) Membrane Characteristics
- Non-sterile capsule configuration supports applications where terminal sterilization is not required or where the user will perform site-specific sterilization by autoclaving.
- Maximum operating temperature of 80 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.
- Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.
- PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
- Capsule holdup volume of 60 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
Key Capsule Construction Features
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. In particular, for laboratories processing cell culture media, buffers, or biological preparations, PES capsule construction delivers the combination of low binding, high throughput, and validated retention that your quality system depends on. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.
Sterilization Guidance
Non-sterile delivery accommodates applications where sterility is not required, while the all-polypropylene construction provides the option for autoclave sterilization when aseptic processing is specified.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 47.9psi
- Compliance Standards
- ISO 9001
- Connection Type
- 1/4 - 3/8 in. stepped hose barb
- Construction
- Polypropylene
- Diameter
- 72mm
- Dimensions
- 72mm x 142mm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 1200cm²
- Flow Rate
- 2.5 L/min at 0.1 bar
- Holdup Volume
- 60mL
- Inlet Connection
- 1/4 - 3/8 in. Stepped Hose Barb
- Length
- 142mm
- Material
- PES
- Max Batch Volume
- <50L
- Maximum Operating Pressure
- 75.4psi
- Maximum Operating Temperature (°C)
- 80°C
- Outlet Connection
- 1/4 - 3/8 in. Stepped Hose Barb
- Pack Count
- 1
- Pore Size (µm)
- 0.2
- Prefilter (Yes/No)
- No
- Sterility
- Nonsterile
- Sterilization
- Autoclavable at 121°C for 30 mins
- Vent (Yes/ No)
- Yes
- Weight
- 0.49
- Wettability
- Hydrophilic
- Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
- Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
- Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
- Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
- Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
- Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.