Featuring a low-binding polyethersulfone (PES) membrane with a 30K molecular weight cut-off (MWCO), these 15mL centrifugal filter units deliver fast, gentle concentration and purification of proteins and other macromolecules. The hydrophilic PES membrane handles a maximum sample volume of 5mL and reduces it to a final concentrate volume of 40 to 100 microliters, while the conical format integrates a filter cartridge into a polypropylene tube for direct spin-and-recover workflows. Each white-capped unit is supplied nonsterile and packaged 24 per box with 4 boxes per case.
Key PES Membrane Characteristics
- Hydrophilic structure wets out readily for consistent flow and reproducible recovery.
- 30K MWCO size exclusion retains target macromolecules above the cut-off while passing salts and smaller solutes.
- Low protein and nucleic acid binding supports high sample recovery of concentrated material.
- High-flux PES medium provides rapid filtration to shorten spin times.
Key Construction Characteristics
- Filter housing: Acrylonitrile Butadiene Styrene (ABS) filter cartridge with a polypropylene (PP) conical receiver tube.
- Format: 15mL conical tube with a 5mL maximum sample volume and a 40 to 100 microliter final concentrate volume.
- Centrifugal force: rated to 3,000 g in a swinging bucket rotor and 7,500 g in a fixed angle rotor.
- Operating temperature: 0 to 40 degrees C.
- Closure and packaging: white cap, nonsterile, 24 units per box, 4 boxes per case.
The vertical membrane geometry and conical design maintain high flow rates and protect sample integrity throughout processing. The dead-stop pocket helps prevent over-concentration to dryness, preserving labile targets and ensuring reliable, repeatable recovery for downstream analysis.
- Capacity
- 15 mL
- Color
- White
- Construction
- Acrylonitrile Butadiene Styrene (ABS) filter cartridge with Polypropylene (PP) conical tube
- Holdup Volume
- 40-100 µl final concentrate volume
- Material
- Polyethersulfone (PES)
- Max Batch Volume
- 5 mL
- Maximum Operating Temperature (°C)
- 40
- MWCO(Da)
- 30000
- Pack Count
- 96
- Sterility
- Nonsterile
- Vial Cap Type
- White Cap
- Wettability
- Hydrophilic
- Protein Concentration Concentrates dilute protein solutions up to 5mL down to a 40 to 100 microliter retentate while retaining species above the 30K cut-off.
- Buffer Exchange Supports rapid buffer exchange and diafiltration of macromolecules using the low-binding PES membrane.
- Desalting Removes salts and small solutes below the 30K MWCO while retaining target proteins and biomolecules.
- Molecule Purification Purifies enzymes, antibodies, and similar macromolecules from lower molecular weight contaminants.
- Protein Fractionation Separates macromolecules by size using the 30K MWCO membrane for fractionation workflows.
- Sample Preparation Prepares concentrated biological samples for downstream chromatography, electrophoresis, and analytical assays.