Tisch
PES Syringe Filters w/ 3 Pre-Filters, 0.45 um, 25mm, 100/Pk SKU: SF18304

Polyethersulfone (PES) Syringe Filters - SF18304

Featuring advanced polyethersulfone membrane technology with triple-layer glass fiber prefiltration for maximum throughput in challenging samples. A 0.45µm pore configuration delivers exceptional clarification performance while three graduated prefilters dramatically extend membrane life with heavily particulated solutions. Tisch Scientific combines hydrophilic PES membranes with innovative multi-stage prefiltration architecture to achieve industry-leading flow rates and capacity.

Key Polyethersulfone (PES) Membrane Characteristics

• Naturally hydrophilic membrane ensures immediate wetting without surfactants or pre-treatment
• Exceptional chemical compatibility withstands aggressive solvents and pH extremes from 1-14
• Low protein binding properties preserve sample integrity and prevent analyte loss
• 0.45µm pore size provides reliable clarification and coarse particulate removal
• Autoclavable construction enables sterilization at 121°C for 30 minutes when required

Key Construction Characteristics

• Triple glass fiber prefilter layers provide graduated particulate retention, maximizing capacity
• Dual Luer-Lok/Luer Slip connectivity accommodates all standard syringe configurations
• Reinforced polypropylene housing withstands 87psi burst pressure for secure operation
• 100µl holdup volume minimizes sample loss when processing valuable or limited samples

SF18304 syringe filters achieve exceptional 65ml/min flow rates through an optimized 4.08cm² active membrane area, dramatically accelerating your filtration workflows even with challenging samples. Triple-layer glass fiber prefiltration technology provides unmatched protection against membrane fouling, consistently delivering 50ml throughput volumes while maintaining 31.91psi bubble point specifications. Autoclave compatibility at 121°C offers flexibility for your applications requiring sterility, transforming nonsterile units into validated sterile filters for critical laboratory processes.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

31.91psi

Burst Pressure (psi)

87psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

65ml

Holdup Volume

100μL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-160μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

GF

Sterility

Nonsterile

Sterilization

Autoclave 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophilic

• Sample Clarification Applications - Removes suspended particles from heavily loaded cell lysates and tissue homogenates with high debris content
• HPLC Sample Preparation - Protects chromatography columns from particulate damage in complex matrices with high solid content and turbidity
• Cell Culture Media Processing - Clarifies serum-containing media and supplements while preserving essential growth factors and nutrients
• Environmental Sample Filtration - Filters soil extracts, wastewater, and sediment samples containing high particulate loads for analysis
• Protein Solution Clarification - Gently clarifies viscous protein preparations while maintaining biological activity and structural integrity
• Pharmaceutical Testing Applications - Prepares samples for dissolution testing and content uniformity analysis of suspension formulations