PES Capsule Filter, 1.20 um, 72mm x 115mm, 1/4 in. MNPT, Nonsterile, 1/Pk SKU: SF14923

Polyethersulfone (PES) Capsule Filters - SF14923

PES capsule filters combine asymmetric membrane architecture with ultra-low protein adsorption, maximizing throughput while preserving the biological activity of filtered solutions. PES membrane chemistry delivers broad pH compatibility from 1 to 14, supporting filtration of buffers, media, and cleaning solutions through a single capsule platform without material degradation. The result is a streamlined filtration step that integrates directly into fluid transfer systems, reducing hold times and minimizing the manual handling that compromises sterility assurance.

Key Polyethersulfone (PES) Membrane Characteristics

• Single-membrane construction simplifies integrity test interpretation, as the bubble point and diffusion flow values correspond directly to the rated retention membrane without prefilter interference.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.
• Rated for operating pressures up to 75.4 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.

Key Capsule Construction Features

• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.

From method development through scale-up to production, your capsule filter choice defines the balance between membrane performance, process integration, and the regulatory documentation trail that supports each filtration event. When your filtration protocol demands both validated retention and maximum product recovery, PES membrane architecture balances performance with the low-adsorption surface chemistry your biologics require. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

13.1psi

Compliance Standards

ISO 9001

Connection Type

1/4 in. MNPT

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 115mm

Filling Bell (Yes/ No)

No

Filtration Area

1000cm²

Flow Rate

14.5 L/min at 0.1 bar

Holdup Volume

60mL

Inlet Connection

1/4 in. MNPT

Length

115mm

Material

PES

Max Batch Volume

＜50L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

1/4 in. MNPT

Pack Count

1

Pore Size (µm)

1.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.42

Wettability

Hydrophilic

• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.