PES Capsule Filter, 0.10um, 72mm x 100mm, 3/8 in. Hose Barb, Nonsterile, 1/Pk SKU: SF14940

Polyethersulfone (PES) Capsule Filters - SF14940

From buffer preparation through biologics processing, PES capsule filters provide the membrane performance and single-use convenience required by modern pharmaceutical workflows. Underpinning this performance, the pleated PES membrane pack maximizes effective filtration area within the capsule housing, sustaining high flow rates through large batch volumes while inherent hydrophilicity ensures immediate wetting without alcohol pre-treatment. The result is a streamlined filtration step that integrates directly into fluid transfer systems, reducing hold times and minimizing the manual handling that compromises sterility assurance.

Key Polyethersulfone (PES) Membrane Characteristics

• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• The 75.4 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• The single membrane configuration is appropriate for pre-clarified feed streams where upstream particulate removal has already reduced the contaminant load to levels within the capsule's dirt-holding capacity.
• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.

Key Capsule Construction Features

• Polypropylene housing materials meet FDA requirements for food contact under 21 CFR 177 and satisfy USP Class VI biocompatibility standards for pharmaceutical applications.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. If your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Non-sterile delivery accommodates applications where sterility is not required, while the all-polypropylene construction provides the option for autoclave sterilization when aseptic processing is specified.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

58psi

Compliance Standards

ISO 9001

Connection Type

3/8 in. hose barb

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 100mm

Filling Bell (Yes/ No)

No

Filtration Area

500cm²

Flow Rate

0.6 L/min at 0.1 bar

Holdup Volume

25mL

Inlet Connection

3/8 in. Hose Barb

Length

100mm

Material

PES

Max Batch Volume

＜20L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

3/8 in. Hose Barb

Pack Count

1

Pore Size (µm)

0.1

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.25

Wettability

Hydrophilic

• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.