PES Capsule Filter, 0.22um, 72mm x 100mm, 3/8 in. Hose Barb, Nonsterile, 1/Pk SKU: SF14950

Polyethersulfone (PES) Capsule Filters - SF14950

PES capsule filters address the growing demand for single-use, validated filtration devices that integrate directly into pharmaceutical and biopharmaceutical fluid transfer systems. Underpinning this performance, asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. Accordingly, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

• Maximum operating pressure of 75.4 psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• The 25 milliliter holdup volume reflects the capsule's internal fluid path geometry, relevant to recovery calculations for precious samples and small-batch pharmaceutical formulations.
• Non-sterile configuration accommodates laboratory and industrial applications where the capsule filter serves a clarification or protection function rather than a sterilizing-grade barrier role.
• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.

Key Capsule Construction Features

• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

As single-use filtration continues to replace reusable housings across pharmaceutical and laboratory environments, your capsule filter selection determines both the quality of the filtrate and the efficiency of the workflow. When your filtration protocol demands both validated retention and maximum product recovery, PES membrane architecture balances performance with the low-adsorption surface chemistry your biologics require. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

47.9psi

Compliance Standards

ISO 9001

Connection Type

3/8 in. hose barb

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 100mm

Filling Bell (Yes/ No)

No

Filtration Area

500cm²

Flow Rate

1.26 L/min at 0.1 bar

Holdup Volume

25mL

Inlet Connection

3/8 in. Hose Barb

Length

100mm

Material

PES

Max Batch Volume

＜20L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

3/8 in. Hose Barb

Pack Count

1

Pore Size (µm)

0.22

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.25

Wettability

Hydrophilic

• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.