PES Capsule Filter, 0.45um, 72mm x 95mm, 1/4 - 3/8 in. Stepped Hose Barb, Nonsterile, 1/Pk SKU: SF14955

Polyethersulfone (PES) Capsule Filters - SF14955

Ultra-low protein binding and broad pH compatibility from 1 to 14 make PES capsule filters the preferred membrane choice for processing biological solutions at production scale. Asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. The outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
• The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.
• Maximum operating temperature of 80 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.
• Non-sterile capsules support autoclave sterilization where the membrane and housing materials permit, allowing users to prepare devices according to their own validated sterilization protocols.
• Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.

Key Capsule Construction Features

• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. If your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

26.1psi

Compliance Standards

ISO 9001

Connection Type

1/4 - 3/8 in. Stepped Hose Barb

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 95mm

Filling Bell (Yes/ No)

No

Filtration Area

500cm²

Flow Rate

2.2 L/min at 0.1 bar

Holdup Volume

25mL

Inlet Connection

1/4 - 3/8 in. Stepped Hose Barb

Length

95mm

Material

PES

Max Batch Volume

＜20L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

1/4 - 3/8 in. Stepped Hose Barb

Pack Count

1

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.24

Wettability

Hydrophilic

• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.