Polyethersulfone (PES) Capsule Filters - SF14957
PES capsule filters combine asymmetric membrane architecture with ultra-low protein adsorption, maximizing throughput while preserving the biological activity of filtered solutions. Supporting this capability, asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. As designed, the result is a filtration workflow that scales efficiently from method development through production, delivering consistent retention performance across the full range of capsule effective filtration areas.
Key Polyethersulfone (PES) Membrane Characteristics
- The single-layer configuration delivers efficient filtration of clean solutions at lower differential pressures than dual-layer alternatives, supporting gravity-feed and low-pressure applications.
- PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
- The 80 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
- PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
- PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
Key Capsule Construction Features
- Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
As single-use filtration continues to replace reusable housings across pharmaceutical and laboratory environments, your capsule filter selection determines both the quality of the filtrate and the efficiency of the workflow. For laboratories processing cell culture media, buffers, or biological preparations, PES capsule construction delivers the combination of low binding, high throughput, and validated retention that your quality system depends on. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.
Sterilization Guidance
Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 13.9psi
- Compliance Standards
- ISO 9001
- Connection Type
- 1/4 in. MNPT
- Construction
- Polypropylene
- Diameter
- 72mm
- Dimensions
- 72mm x 172mm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 2100cm²
- Flow Rate
- 13.2 L/min at 0.1 bar
- Holdup Volume
- 89mL
- Inlet Connection
- 1/4 in. MNPT
- Length
- 172mm
- Material
- PES
- Max Batch Volume
- <100L
- Maximum Operating Pressure
- 75.4psi
- Maximum Operating Temperature (°C)
- 80°C
- Outlet Connection
- 1/4 in. MNPT
- Pack Count
- 1
- Pore Size (µm)
- 1.2
- Prefilter (Yes/No)
- No
- Sterility
- Nonsterile
- Sterilization
- Autoclavable at 121°C for 30 mins
- Vent (Yes/ No)
- Yes
- Weight
- 0.49
- Wettability
- Hydrophilic
- Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
- Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
- Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
- Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
- Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
- Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.