Tisch
Polypropylene Syringe Filters, 0.45um, 25mm, Double Luer Lock, PP Housing, Nonsterile, 100/Pk SKU: SPEC18188

Polypropylene (PP) Syringe Filters - SPEC18188

Clarifying samples containing particulates while maintaining chemical compatibility with aggressive solvents challenges many laboratory workflows. Polypropylene membrane technology addresses this problem through its exceptional resistance to acids, bases, alcohols, and challenging organic solvents that degrade alternative materials. The 0.45 µm pore size removes particulates effectively while allowing dissolved components to pass through, making it ideal for sample preparation before instrumental analysis. You benefit from low protein binding characteristics that maximize analyte recovery in critical assays where sample loss compromises accuracy.

Key Membrane Characteristics

• 0.45 µm polypropylene membrane provides efficient clarification of particulate-laden samples with broad chemical compatibility across solvent classes
• 4.9 cm² filtration area in the 25mm diameter configuration delivers 100 ml throughput capacity for routine sample processing
• Hydrophobic surface properties naturally resist aqueous wetting while allowing organic solvents and non-polar solutions to flow efficiently
• Flow rate of 320 ml/min at 10 psi enables rapid sample processing, doubling the throughput speed of smaller pore sizes
• Maximum operating pressure of 72.5 psi with 116 psi burst pressure accommodates viscous samples and challenging matrix compositions

Key Construction Characteristics

• Polypropylene housing construction throughout the assembly ensures uniform chemical resistance from inlet to outlet connections
• 100 µL holdup volume minimizes sample waste, particularly valuable when processing expensive reagents or volume-limited specimens
• Double luer lock connections on both inlet and outlet ports prevent disconnection during filtration of pressurized or viscous samples
• Maximum operating temperature of 80°C supports warm solvent filtration and thermally sensitive sample processing requirements

Your nonsterile filters arrive ready for autoclave sterilization at 121°C for 30 minutes or gamma irradiation at 5 kGy for 8 hours, integrating seamlessly into your laboratory protocols. The hydrophobic polypropylene membrane maintains performance across diverse chemical environments, though extended contact with esters, hexane, toluene, benzene, and dichloromethane should be avoided. Each filter combines cost-effective operation with reliable particulate removal, delivering consistent clarification results for your routine analytical workflows.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

NA

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Polypropylene (PP)

Diameter

25mm

Dimensions (W x D x H)

21.8mmx28.6mm

Material

Polypropylene (PP)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

80℃

Pack Count

100

Pore Size (µm)

0.45

Sterility

Nonsterile

Weight

0.58

Wetability

Hydrophobic

• HPLC Sample Preparation - Particulate removal from injection samples, protecting columns and guard cartridges from fouling and pressure buildup
• Organic Solvent Clarification - Purification of alcohols, ketones, and other aggressive solvents incompatible with polyamide or cellulosic membranes
• Protein Assay Samples - Clarifying biological matrices while maintaining low protein binding for accurate quantification in research applications
• UV-Vis Spectroscopy Prep - Removing particulates that scatter light and interfere with absorbance measurements in analytical laboratories
• Cell Culture Sampling - Clarification of fermentation broths and culture media for downstream analysis without affecting dissolved protein content
• Peptide Solution Filtration - Processing peptide-based formulations where particulate removal is required without compromising peptide recovery rates