PTFE Capsule Filter, 0.22 um, 72mm x 115mm, 1/4 in. MNPT, Nonsterile, 1/Pk SKU: SF15002

PTFE Capsule Filters - SF15002

From HPLC mobile phase preparation to process gas venting, PTFE capsule filters handle the chemically aggressive applications where other membrane materials degrade or fail. Developed with critical workflows in mind, PTFE membrane stability at elevated temperatures supports both liquid filtration and sterile gas venting applications, with capsule construction rated for the operating pressures encountered in process-scale systems. For this reason, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key PTFE Membrane Characteristics

PTFE capsule filters maintain mechanical integrity and retention performance at temperatures exceeding those tolerated by PES, PVDF, or nylon membranes, supporting high-temperature process filtration.
The hydrophobic PTFE membrane serves both liquid solvent filtration and sterile gas venting applications, with alcohol pre-wetting required only for aqueous solution processing.
Capsule holdup volume of 60 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
Rated for operating pressures up to 75.4 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
Chemical inertness of the PTFE membrane ensures that filtered solvents and gases pass through without extractable contamination, meeting the purity requirements of HPLC mobile phase preparation and analytical applications.

Key Capsule Construction Features

Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. When your application requires a membrane that withstands both chemical attack and elevated temperatures, PTFE construction delivers the durability your process conditions require without sacrificing retention performance. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.