PTFE Capsule Filter, 0.45um, 72mm x 115mm, 1/4 in. MNPT, Nonsterile, 1/Pk SKU: SF15003

PTFE Capsule Filters - SF15003

The broad chemical compatibility and thermal resistance of PTFE capsule filters make them a reliable choice for filtration tasks spanning organic chemistry, pharmaceutical manufacturing, and process gas handling. The chemically inert PTFE membrane within the capsule housing resists degradation by virtually all organic solvents, strong acids, and alkaline solutions, enabling filtration of the most aggressive process fluids. In turn, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key PTFE Membrane Characteristics

• The hydrophobic PTFE membrane serves both liquid solvent filtration and sterile gas venting applications, with alcohol pre-wetting required only for aqueous solution processing.
• Chemical inertness of the PTFE membrane ensures that filtered solvents and gases pass through without extractable contamination, meeting the purity requirements of HPLC mobile phase preparation and analytical applications.
• PTFE membrane capsules resist degradation by virtually all organic solvents, strong acids, bases, and oxidizing agents, providing universal chemical compatibility for aggressive filtration applications.
• Rated for operating pressures up to 75.4 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
• The 60 milliliter holdup volume reflects the capsule's internal fluid path geometry, relevant to recovery calculations for precious samples and small-batch pharmaceutical formulations.

Key Capsule Construction Features

• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. For laboratories and production facilities filtering HPLC mobile phases, aggressive chemicals, or sterile gases, PTFE capsule filters provide the chemical inertness your purity standards demand. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

7.3psi

Compliance Standards

ISO 9001

Connection Type

1/4 in. MNPT

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 115mm

Filling Bell (Yes/ No)

No

Filtration Area

1000cm²

Flow Rate

3.37 L/min at 0.1 bar

Holdup Volume

60mL

Inlet Connection

1/4 in. MNPT

Length

115mm

Material

PTFE

Max Batch Volume

＜50L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

1/4 in. MNPT

Pack Count

1

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.42

Wettability

Hydrophobic

• Solvent Filtration - Chemical-resistant filtration of HPLC mobile phases, aggressive organic solvents, and corrosive reagent solutions.
• Solvent Recovery - Clarification of recycled organic solvents to remove particulates accumulated during previous processing operations.
• Tank Venting - Hydrophobic membrane barrier prevents microbial ingress while allowing pressure equalization in process tank headspaces.
• Chemical Processing - Filtration of strong acids, bases, and aggressive organic chemicals that degrade PES, PVDF, and nylon membranes.
• HPLC Preparation - Particle removal from organic and mixed mobile phases prior to high-performance liquid chromatography analysis.
• Air Filtration - Point-of-use filtration of compressed air and nitrogen gas streams supplying clean manufacturing environments.