Tisch
PTFE Syringe Filters w/ GD-4 Pre-Filter, 0.22 um, 25mm, Nonsterile, 100/Pk SKU: GD17035

Polytetrafluoroethylene (PTFE) Syringe Filters - GD17035

When you're filtering aggressive solvents and corrosive reagents, you need the broadest chemical resistance available. The 0.22µm PTFE filters with integrated GD-4 glass fiber prefilters handle everything from strong acids to challenging organics like DMF and chloroform. The hydrophobic membrane removes bacteria from non-aqueous solutions while the glass fiber layer captures large particles upstream, extending membrane life in high-particulate samples.

Key Polytetrafluoroethylene (PTFE) Membrane Characteristics

• Hydrophobic membrane requires pre-wetting with alcohol for aqueous solutions
• Universal chemical resistance withstands all organic solvents, acids, and bases
• Exceptional thermal stability maintains integrity at 60°C continuous operation
• 0.22µm pore size removes bacteria from non-aqueous solutions in sterile-grade applications
• Autoclavable construction enables sterilization at 121°C for 30 minutes when required

Key Construction Characteristics

• GD-4 glass fiber prefilter extends membrane life by capturing larger particulates upstream
• Dual Luer-Lok/Luer Slip connectivity accommodates all standard syringe configurations
• Polypropylene housing withstands 87psi burst pressure for secure high-pressure operations
• 100µl holdup volume minimizes sample loss when filtering valuable or limited reagents

You can autoclave these filters at 121°C for 30 minutes when your protocols require pre-sterilization, giving you flexibility in critical applications. The glass fiber prefilter captures large particles before they reach the PTFE membrane, extending filter life when you're processing high-particulate samples. Process up to 100ml throughput with the 4.08cm² filtration area, and the 18ml/min flow rate keeps your work moving without sacrificing chemical resistance across acids, bases, and organic solvents.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

17.4psi

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

18ml

Holdup Volume

100μL

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.22

Sterility

NonSterile

Sterilization

Autoclave 121°C for 30min/ Gamma 25kGy

Volume Throughput (ml)

100ml

Weight

0.70

Wetability

Hydrophobic

• Aggressive Solvent Filtration - Handles DMF, DMSO, THF, and chloroform where other membranes degrade, protecting analytical equipment downstream
• Sterile Filtration - Removes bacteria from non-aqueous pharmaceutical solutions and organic reagents requiring sterile-grade processing
• HPLC Sample Preparation - Protects chromatography columns from particulates in organic mobile phases while maintaining chemical compatibility
• Air and Gas Venting - Hydrophobic membrane permits gas passage while blocking aqueous contamination in laboratory equipment and vessels
• Strong Acid Handling - Filters concentrated HCl, H2SO4, and HNO3 without membrane degradation in chemical synthesis and analytical workflows
• Protein Precipitation Cleanup - Clarifies samples after TCA, acetonitrile, or methanol precipitation in proteomics sample preparation