Tisch
PTFE Syringe Filters, 0.45um, 25mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF14475

Polytetrafluoroethylene (PTFE) Syringe Filters - SF14475

Featuring hydrophobic PTFE membrane technology in sterile packaging for aggressive organic solvent clarification requiring contamination-free processing. A 0.45µm pore configuration delivers efficient particulate removal while maintaining complete chemical inertness to concentrated acids, bases, and challenging reagents. Tisch Scientific combines ultra-resistant PTFE membranes with optimized 25mm construction to provide certified sterile clarification of chemically aggressive samples at production scale.

Key Polytetrafluoroethylene (PTFE) Membrane Characteristics

• Hydrophobic membrane requires alcohol pre-wetting for aqueous solution compatibility
• Universal chemical resistance handles all organic solvents, acids, and bases without degradation
• Exceptional thermal stability maintains performance at 60°C continuous operating conditions
• 0.45µm pore size provides reliable clarification and coarse particulate removal
• Sterile individual packaging ensures contamination-free filtration for sensitive applications

Key Construction Characteristics

• Polypropylene housing delivers chemical resistance while withstanding 87psi burst pressure
• Dual Luer-Lok/Luer Slip compatibility accommodates all standard syringe configurations
• Standard 25mm diameter optimizes flow rate and capacity for routine sterile processing
• 100µL holdup volume minimizes loss when filtering valuable sterile reagents

SF14475 syringe filters achieve exceptional 35ml/min flow rates through a 4.08cm² active membrane area, accelerating your sterile sample processing even with viscous organic solvents. Outstanding 100ml throughput capacity maximizes your laboratory efficiency when filtering challenging matrices requiring certified sterility. Pre-sterilized units maintain 7.25psi bubble point integrity in absolute ethyl alcohol, ensuring reliable performance for your critical applications demanding both absolute chemical resistance and validated contamination-free processing.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

7.25(absolute ethyl alcohol ）

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

35ml

Holdup Volume

100μL

Incompatibility

Aqueous samples without rewetting

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.45

Sterility

Sterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

100ml

Weight

0.88

Wetability

Hydrophobic

• Aggressive Solvent Clarification - Removes particulates from THF, DMF, and DMSO for sterile aseptic cell culture workflows and biological applications
• HPLC Sample Preparation - Provides sterile particulate removal from samples in organic mobile phases, protecting chromatography instrumentation
• Strong Acid Sterile Filtration - Enables sterile handling of concentrated HCl, H₂SO₄, and HNO₃ for trace analysis and ultra-clean analytical procedures
• Protein Precipitation Cleanup - Delivers sterile clarification following TCA or organic solvent precipitation in proteomics sample preparation
• Tissue Culture Processing - Provides sterile filtration of organic solvents for cell fixation and extraction protocols in biological research
• Pharmaceutical Dissolution Testing - Prepares sterile samples for dissolution testing in aggressive media conditions, meeting quality control standards