Tisch
PTFE Syringe Filters, 0.22 um, 33mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF14476

Polytetrafluoroethylene (PTFE) Syringe Filters - SF14476

Featuring hydrophobic PTFE membrane technology in sterile packaging for high-volume aggressive organic solvent filtration requiring complete microbiological control. A 0.22µm pore configuration ensures sterile-grade bacterial removal while maintaining absolute chemical inertness to concentrated acids, bases, and challenging solvents. Tisch Scientific combines ultra-resistant PTFE membranes with large 33mm construction to maximize throughput for production-scale sterile filtration of chemically aggressive samples.

Key Polytetrafluoroethylene (PTFE) Membrane Characteristics

• Hydrophobic membrane requires alcohol pre-wetting for aqueous solution compatibility
• Universal chemical resistance withstands all organic solvents, acids, and bases without degradation
• Superior thermal stability maintains integrity at 60°C continuous operating conditions
• 0.22µm absolute pore rating guarantees complete bacterial and microorganism removal
• Sterile individual packaging ensures contamination-free filtration for critical applications

Key Construction Characteristics

• Polypropylene housing provides chemical resistance while withstanding 87psi burst pressure
• Dual Luer-Lok/Luer Slip connections ensure universal compatibility with standard syringes
• Large 33mm diameter maximizes filtration area for high-volume sterile sample processing
• 100µl holdup volume minimizes loss despite a larger format when filtering valuable reagents

SF14476 syringe filters deliver 29.5ml/min flow rates through an expanded 4.9cm² active membrane area, optimizing your high-volume sterile filtration workflows for aggressive chemical applications. Exceptional 120ml throughput capacity supports your production-scale requirements while maintaining certified sterility throughout processing. Pre-sterilized units maintain 17.4psi bubble point integrity in absolute ethyl alcohol, ensuring reliable bacterial retention for your critical large-volume applications demanding both absolute chemical resistance and validated microbiological safety.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

17.4(absolute ethyl alcohol ）

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

33mm

Filtration Area

4.9cm²

Flow Rate

29.5ml

Holdup Volume

100μL

Incompatibility

Aqueous samples without rewetting

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.22

Sterility

Sterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

120ml

Wetability

Hydrophobic

• Aggressive solvents - High-volume sterile filtration of DMF, DMSO, THF, acetonitrile for production-scale synthesis and purification
• Sterile filtration - Complete bacterial removal from bulk non-aqueous APIs, excipients, and pharmaceutical intermediates in organic solvents
• Scale-up processing - Sterile filtration of 50-120ml volumes in organic synthesis, natural product extraction, and chemical purification workflows
• Strong acid filtration - Sterile handling of concentrated HCl, H2SO4, HNO3, and TFA for analytical method development and trace metal analysis
• Tissue culture - Bulk sterile filtration of methanol, ethanol, and chloroform for cell fixation, permeabilization, and lipid extraction
• Pharmaceutical manufacturing - Production-scale sterile filtration of heat-labile APIs dissolved in aggressive solvents requiring aseptic processing