Tisch
PTFE Syringe Filters, 0.22um, 4mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF18243

Polytetrafluoroethylene (PTFE) Syringe Filters - SF18243

Featuring hydrophobic PTFE membrane technology with 0.22µm pore size in pre-sterilized packaging for sterile filtration of microscale samples in aggressive solvent systems. Ultra-compact 4mm diameter filters minimize sample loss with just 1µl holdup volume while ensuring complete bacterial removal. Polypropylene housing construction maintains chemical compatibility at pressures up to 87psi for reliable microscale sterilization.

Key Polytetrafluoroethylene (PTFE) Membrane Characteristics

• Hydrophobic membrane design provides sterile filtration of organic solvents, acids, and bases without degradation
• Sterile-grade 0.22µm pore size removes bacteria and microorganisms from precious samples for sterilizing filtration applications
• Pre-sterilized by gamma irradiation eliminates preparation steps for critical aseptic applications
• Superior chemical resistance from strong carbon-fluorine bonds withstands aggressive solvents and reagents
• Membrane thickness of 80-140µm optimizes retention efficiency while maintaining flow for ultra-small volumes

Key Construction Characteristics

• Polypropylene housing ensures broad chemical compatibility with organic and inorganic solvents
• Microscale 4mm diameter with 0.125cm² filtration area, ideal for ultra-low volume sterile applications
• Industry-leading 1µl holdup volume maximizes recovery of expensive or irreplaceable samples
• Luer-Lok/Luer Slip dual connection compatibility works with precision syringes and microvolume systems

When sterility matters for your irreplaceable samples, you get exceptional recovery with just 1µl holdup volume—almost nothing stays behind. The 0.7ml flow rate gives you controlled processing without rushing through critical sterilization steps. Since this arrives pre-sterilized, you skip preparation entirely and start filtering immediately. Bubble point testing at 17.4psi with ethyl alcohol confirms your membrane integrity before every batch, so you know the 0.22μm structure is intact. For microscale work where both sterility and sample conservation are non-negotiable, you're getting reliable performance in the smallest practical format.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

17.4(absolute ethyl alcohol ）

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

4mm

Filtration Area

0.125cm²

Flow Rate

0.7ml

Holdup Volume

1μL

Incompatibility

Aqueous samples without rewetting

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-140μm

Pack Count

100

Pore Size (µm)

0.22

Sterility

Sterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

1ml

Weight

0.33

Wetability

Hydrophobic

• Microscale Sterile Filtration - Removes bacteria from microliters of precious cell culture media reagents and recombinant growth factors
• NMR Sample Sterilization - Ensures sterility of deuterated solvents and expensive isotope-labeled compounds for nuclear magnetic resonance analysis
• High-Value API Processing - Sterilizes costly active pharmaceutical ingredients while minimizing material loss during development workflows
• Mass Spectrometry Prep - Eliminates bacterial contamination from LC-MS injection samples, preventing column degradation and ion source fouling
• Protein Crystal Solutions - Sterilizes crystallization screening buffers and concentrated protein solutions for structural biology research applications
• Analytical Method Development - Prepares sterile limited-volume test samples for sensitive bioassay validation and optimization research studies