Tisch
Hydrophilic PVDF Syringe Filters, 0.22 um, 13mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF17389

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17389

Pharmaceutical and biotechnology laboratories require sterilization technology that can process small-volume aqueous biological samples with immediate wettability while maintaining validated bacterial retention and minimal holdup across cell culture media, buffer systems, and protein formulations commonly encountered in pharmaceutical manufacturing and research workflows. Advanced hydrophilic polyvinylidene fluoride membrane technology with 0.22 µm pore size and single-layer design delivers sterile-grade bacterial elimination through naturally wettable surface chemistry that eliminates pre-treatment steps while preserving low protein binding characteristics essential for therapeutic protein processing. Furthermore, the compact 13mm diameter configuration with 0.92 cm² filtration area enables efficient sterilization of 1-10 ml sample volumes, making this design ideal for pharmaceutical quality control and biological research applications requiring both microbial control and maximum sample recovery through minimal holdup without prefilter-related retention.

Key Hydrophilic PVDF Membrane Characteristics

• Naturally wettable hydrophilic surface eliminates alcohol pre-wetting requirements, enabling immediate aqueous sample filtration without preparatory solvent steps
• 0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination for pharmaceutical applications
• Low protein binding characteristics maintain the concentration of therapeutic proteins and biomolecules during sterilization, minimizing product loss in biopharmaceutical processing
• Chemical compatibility resists degradation from biological buffers and aqueous solutions while maintaining stable operation across pharmaceutical formulation workflows
• Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for sensitive pharmaceutical laboratory applications

Key Construction Characteristics

• 10 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and biological compounds
• Polypropylene housing delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse bioprocessing conditions
• Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining workflow integration into pharmaceutical processing equipment
• Single-layer membrane design without a prefilter provides direct sterile filtration for pre-clarified aqueous samples, reducing holdup volume and maximizing biomolecule recovery

Pharmaceutical and biotechnology laboratories processing small-volume aqueous samples require sterilization technology that combines bacterial retention with immediate wettability and minimal holdup. Hydrophilic PVDF syringe filters deliver 0.22 µm sterile-grade performance through naturally wettable membrane chemistry and single-layer design. Optimized for your challenging pharmaceutical workflows, this filtration solution provides workflow efficiency with validated microbial retention, minimal holdup for maximum recovery, and immediate aqueous sample compatibility for biopharmaceutical manufacturing, cell culture sterilization, and quality control applications requiring both efficient processing and bacterial elimination capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

43.51psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

13mm

Filtration Area

0.92cm²

Flow Rate

5ml

Holdup Volume

10μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

10ml

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Removes bacteria from aqueous culture media and supplements for mammalian cell bioprocessing and research applications
• Biological Buffer Sterilization - Sterilizes phosphate buffers and saline solutions for pharmaceutical manufacturing and laboratory research requiring aseptic conditions
• Therapeutic Protein Filtration - Filters small-volume aqueous protein solutions while maintaining biological activity and concentration in biopharmaceutical processing
• Vaccine Sample Processing - Sterilizes aqueous vaccine formulations and biological samples for pharmaceutical quality control testing in development laboratories
• Water Quality Testing - Provides sterile aqueous samples for microbiological analysis and environmental monitoring in regulatory compliance programs
• Tissue Culture Supplement Filtration - Sterilizes growth factors and serum additives for cell culture applications requiring contamination-free processing