Tisch
Hydrophilic PVDF Syringe Filters, 0.22 um, 13mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF17389

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17389

Pharmaceutical and biotechnology laboratories require sterilization technology for small-volume aqueous biological samples. Users need immediate wettability and validated bacterial retention. Advanced hydrophilic polyvinylidene fluoride membrane technology delivers sterile-grade bacterial elimination. The 0.22 µm pore size ensures safety without pre-treatment steps. A compact 13mm diameter configuration with 0.92 cm² filtration area enables efficient sterilization. Users can process 1-10 ml sample volumes effectively. The design suits pharmaceutical quality control and biological research applications.

Key Hydrophilic PVDF Membrane Characteristics

• Naturally wettable hydrophilic surface eliminates alcohol pre-wetting requirements, enabling immediate aqueous sample filtration without preparatory solvent steps
• 0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination
• Low protein binding characteristics maintain the concentration of therapeutic proteins and biomolecules during sterilization, minimizing product loss
• Chemical compatibility resists degradation from biological buffers and aqueous solutions while maintaining stable operation across pharmaceutical workflows
• Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for sensitive pharmaceutical laboratory applications

Key Construction Characteristics

• 10 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and biological compounds
• Polypropylene housing delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse bioprocessing conditions
• Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining workflow integration into pharmaceutical processing equipment
• Single-layer membrane design without a prefilter provides direct sterile filtration for pre-clarified aqueous samples, reducing holdup volume

Laboratories processing small-volume aqueous samples require specific sterilization technology. It must combine bacterial retention with immediate wettability. Hydrophilic PVDF syringe filters deliver 0.22 µm sterile-grade performance. The naturally wettable membrane chemistry simplifies workflows. Optimized for challenging pharmaceutical workflows, the solution provides efficiency. Users benefit from validated microbial retention and minimal holdup.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

43.51psi

Connection Type

Luer-Lok/Luer Slip

Diameter

13mm

Filtration Area

0.92cm²

Flow Rate

5ml

Holdup Volume

10μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

10ml

Weight

0.19

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Removes bacteria from aqueous culture media and supplements for mammalian cell bioprocessing applications
• Biological Buffer Sterilization - Sterilizes phosphate buffers and saline solutions for pharmaceutical manufacturing requiring aseptic conditions
• Therapeutic Protein Filtration - Filters small-volume aqueous protein solutions while maintaining biological activity via low protein binding
• Vaccine Sample Processing - Sterilizes aqueous vaccine formulations and biological samples for pharmaceutical quality control testing
• Water Quality Testing - Provides sterile aqueous samples for microbiological analysis and environmental monitoring compliance programs
• Culture Supplement Filtration - Sterilizes growth factors and serum additives for cell culture applications requiring contamination-free processing