Tisch
Hydrophilic PVDF Syringe Filters, 0.22 um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF17390

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17390

Hydrophilic polyvinylidene fluoride membrane technology delivers sterile-grade bacterial retention for aqueous biological samples. The 0.22 µm pore size ensures microbial elimination without pre-wetting steps in pharmaceutical workflows. Laboratories across biotechnology research utilize these 25mm filters for efficient processing. Specialized surface chemistry enables immediate filtration of aqueous samples by eliminating alcohol preparation. The membrane maintains low protein binding characteristics essential for therapeutic protein sterilization. A 2.98 cm² filtration area maximizes recovery of valuable pharmaceutical formulations. Users process volumes between 10-100 ml efficiently. The 100 µL holdup volume ensures minimal loss during quality control applications.

Key Hydrophilic PVDF Membrane Characteristics

• Naturally wettable surface eliminates alcohol pre-wetting requirements for aqueous processing, enabling immediate filtration of biological samples
• 0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial control
• Low protein binding affinity maintains concentration of therapeutic proteins and biomolecules during sterilization, minimizing product loss
• Chemical compatibility resists degradation from biological buffers and mild acids while maintaining stable operation across pharmaceutical formulation workflows
• Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for aseptic pharmaceutical applications

Key Construction Characteristics

• 100 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and biological materials
• Polypropylene housing provides structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse conditions
• Dual Luer-Lok and Luer-Slip connections accommodate standard laboratory syringes without adapters, streamlining aseptic transfer procedures
• Single-layer membrane design without a prefilter provides direct sterile filtration for pre-clarified aqueous samples, reducing holdup volume

Laboratories processing medium-volume aqueous samples require sterilization technology combining bacterial retention with immediate wettability. Hydrophilic PVDF syringe filters deliver 0.22 µm performance through naturally wettable membrane chemistry. The solution provides operational excellence for demanding pharmaceutical workflows. Users benefit from immediate aqueous sample processing and validated microbial retention. Low protein binding supports biopharmaceutical manufacturing and quality control applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

43.51psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

2.98cm²

Flow Rate

20ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Removes bacteria from aqueous culture media and biological supplements for mammalian cell bioprocessing
• Biological Buffer Sterilization - Sterilizes phosphate buffers and saline solutions for pharmaceutical manufacturing and laboratory research
• Therapeutic Protein Filtration - Filters aqueous protein solutions while maintaining biological activity and concentration in biopharmaceutical
• Vaccine Sample Processing - Sterilizes aqueous pharmaceutical formulations and biological samples for quality control testing in laboratories
• Water Quality Testing - Provides sterile aqueous samples for microbiological analysis and environmental monitoring in regulatory compliance programs
• Tissue Culture Supplement Filtration - Sterilizes growth factors and serum additives for cell culture, requiring contamination-free processing