Tisch
Hydrophilic PVDF Syringe Filters, 0.45um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF17397

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17397

Biological and pharmaceutical laboratories processing aqueous samples face workflow delays from membrane pre-wetting requirements and protein adsorption that compromises sample integrity, requiring clarification technology that enables immediate aqueous processing while preserving biomolecule concentration through low-binding surface chemistry without bacterial retention specifications. Hydrophilic polyvinylidene fluoride membrane technology with 0.45 µm pore size addresses this challenge through naturally wettable surface that eliminates pre-treatment steps while delivering efficient particulate removal and rapid 32 ml/min flow rates. Additionally, the 25mm diameter design with 2.98 cm² filtration area and 100 µL holdup volume enables processing of 10-100 ml sample volumes, reducing filtration time for routine analytical workflows requiring clarification of biological extracts and aqueous buffer systems.

Key Hydrophilic PVDF Membrane Characteristics

• Naturally wettable hydrophilic surface eliminates methanol or isopropanol pre-wetting steps, enabling immediate aqueous sample filtration without solvent preparation procedures
• 0.45 µm pore size removes particulates from biological samples for chromatography analysis and quality control testing without providing sterile-grade specifications
• Low protein binding characteristics maintain biomolecule concentration during sample preparation, minimizing adsorption losses in pharmaceutical and biotechnology analytical applications
• Chemical compatibility resists degradation from biological buffers and aqueous solutions while maintaining stable operation across analytical laboratory workflows
• Rapid throughput with a 32ml/ min flow rate accelerates the processing of aqueous samples, improving workflow efficiency in high-volume analytical environments

Key Construction Characteristics

• 100 µL holdup volume minimizes loss of valuable biological compounds and analytical standards, maximizing recovery for medium-volume clarification applications
• Polypropylene housing construction delivers structural integrity to 87 psi maximum operating pressure, providing operational confidence for pressurized filtration systems
• Dual Luer-Lok and Luer-Slip connections integrate seamlessly with standard laboratory syringes without adapters, simplifying workflow setup in routine testing
• Single-layer membrane design without a prefilter provides direct filtration for pre-clarified aqueous samples, reducing holdup volume and maximizing biomolecule recovery

Analytical and biotechnology laboratories processing medium-volume aqueous samples require clarification technology that combines rapid processing with minimal protein loss and immediate wettability. Hydrophilic PVDF syringe filters deliver 0.45 µm clarification performance through naturally wettable membrane chemistry and efficient flow characteristics. Engineered to overcome your analytical processing challenges, this filtration solution provides processing confidence via immediate aqueous sample compatibility, low protein binding, and rapid throughput for chromatography preparation, biological sample clarification, and quality control applications requiring reliable particulate removal without bacterial retention capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

21.8psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

2.98cm²

Flow Rate

32ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Wetability

Hydrophilic

• HPLC Mobile Phase Preparation - Clarifies aqueous buffer systems and gradient mixtures for liquid chromatography in pharmaceutical analytical testing
• Biological Sample Clarification - Removes particulates from cell culture supernatants and tissue homogenates for downstream analysis in biotechnology research
• Protein Assay Preparation - Filters biological extracts before spectrophotometric or chromatographic protein quantification for pharmaceutical development
• Water Quality Analysis - Clarifies aqueous environmental samples for dissolved metal analysis and water quality monitoring in regulatory laboratories
• Buffer and Reagent Filtration - Removes particles from laboratory solutions and working standards for analytical chemistry research applications
• Vaccine Sample Processing - Clarifies aqueous biological samples for analytical testing in pharmaceutical quality assurance and development laboratories