Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17398
Laboratories processing aqueous biological samples in high-throughput environments face the dual challenge of maintaining rapid filtration rates while preventing membrane fouling from protein-rich solutions. Hydrophilic polyvinylidene fluoride membrane technology with 0.45 µm pore size addresses this challenge through naturally wettable surface chemistry that eliminates pre-treatment steps and reduces processing time. Additionally, the integrated glass fiber prefilter extends membrane life by capturing particulate matter before it reaches the primary filtration layer, enabling consistent performance across extended sample batches. This dual-layer configuration combines 4.6 cm² filtration area with 100 µL holdup volume, maximizing sample recovery for routine analytical workflows requiring efficient clarification without sterile-grade specifications.
Key Hydrophilic PVDF Membrane Characteristics
- Naturally wettable surface eliminates alcohol pre-wetting requirements, enabling immediate processing of aqueous samples without preparatory steps or solvent waste
- Broad chemical compatibility withstands organic solvents and aggressive pH conditions while maintaining stable operation across diverse analytical applications
- Low protein binding characteristics preserve biomolecule concentration during filtration, minimizing sample loss in protein assays and biological preparations
- 0.45 µm pore size delivers reliable clarification performance for particulate removal in HPLC mobile phase preparation and sample cleanup procedures
- Superior flow characteristics accelerate processing with a 39ml/ min flow rate, reducing filtration time for routine quality control and research applications
Key Construction Characteristics
- 100 µL holdup volume preserves samples by minimizing retention within the filter housing, optimizing yield for valuable biological extracts and analytical standards
- Polypropylene housing withstands temperatures up to 60°C with 87 psi burst pressure, providing operational confidence for pressurized filtration systems
- Dual Luer-Lok and Luer-Slip connections accommodate diverse syringe types without requiring adapters, streamlining workflow integration across laboratory equipment platforms
- Glass fiber prefilter configuration captures coarse particles and extends membrane lifetime, reducing filter consumption in high-particulate sample processing applications
Bioanalytical and pharmaceutical laboratories processing high-volume aqueous samples require clarification technology that balances throughput efficiency with protein recovery. Hydrophilic PVDF syringe filters deliver 0.45 µm clarification performance through naturally wettable membrane chemistry and integrated prefilter protection. Designed for your most demanding sample preparation workflows, this dual-layer technology provides processing confidence via validated chemical resistance, low protein binding, and extended membrane lifetime for routine analytical applications requiring rapid clarification without bacterial retention capabilities.
For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 21.8psi
- Burst Pressure (psi)
- 87psi.
- Connection Type
- Luer-Lok/ Luer Slip
- Construction
- Polypropylene (PP)
- Diameter
- 33mm
- Filtration Area
- 4.6cm²
- Flow Rate
- 39ml
- Holdup Volume
- 100μL
- Incompatibility
- Bases, esters, ethers, ketones, aqueous samples without rewetting
- Material
- Polyvinylidene Fluoride (PVDF)
- Maximum Operating Pressure
- 87psi
- Maximum Operating Temperature (°C)
- 60°C
- Membrane Thickness (µm)
- 100-130μm
- Pack Count
- 100
- Pore Size (µm)
- 0.45
- Prefilter (Yes/No)
- Yes
- Prefilter Material
- GF
- Sterility
- Nonsterile
- Sterilization
- Autoclave at 121°C for 30min/ gamma 25kGy
- Volume Throughput (ml)
- 110ml
- Wetability
- Hydrophilic
- HPLC Mobile Phase Filtration - Removes particulates from aqueous buffer systems and gradient mixtures, protecting chromatography columns from fouling
- Biological Sample Clarification - Processes cell culture supernatants and tissue homogenates for downstream analysis without protein loss or membrane clogging
- Water Quality Testing - Clarifies environmental water samples for dissolved metal analysis and microbial enumeration in regulatory compliance programs
- Protein Assay Sample Preparation - Filters biological extracts before spectrophotometric or chromatographic protein quantification for research applications
- Vaccine and Biologic Processing - Removes aggregates from aqueous formulations during pharmaceutical development and small-scale production campaigns
- Buffer and Reagent Preparation - Clarifies laboratory solutions and working standards for analytical chemistry and biochemistry research environments