Tisch
PVDF Syringe Filters, 0.22um, 25mm, Luer-Lok/Luer Slip, Sterile, 100 /Pk SKU: SF18229

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18229

Pharmaceutical laboratories processing aqueous biological samples face workflow delays from membrane pre-wetting requirements and contamination risks during aseptic transfer procedures, requiring sterilization technology that enables immediate aqueous processing through naturally wettable surface chemistry while delivering validated bacterial retention across cell culture media, buffer systems, and protein formulations. Hydrophilic polyvinylidene fluoride membrane technology with 0.22 µm pore size addresses this challenge through surface modification that eliminates alcohol pre-treatment steps while maintaining sterile packaging for contamination-free handling. Additionally, the 25mm diameter design with 4.08 cm² filtration area and 100 µL holdup volume enables processing of 10-100 ml sample volumes, reducing preparation time for routine pharmaceutical workflows requiring both microbial control and efficient aqueous sample sterilization.

Key Hydrophilic PVDF Membrane Characteristics

Naturally wettable hydrophilic surface eliminates methanol or isopropanol pre-wetting steps, enabling immediate aqueous sample filtration without preparatory procedures
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention including Brevundimonas diminuta, ensuring microbial elimination for pharmaceutical manufacturing
Low protein binding characteristics maintain concentration of therapeutic proteins and biomolecules during sterilization, minimizing product loss in biopharmaceutical processing
Chemical compatibility resists degradation from biological buffers and aqueous solutions while maintaining stable operation across pharmaceutical formulation workflows
Sterile packaging eliminates initial contamination risks for aseptic transfer procedures, supporting GMP compliance requirements in pharmaceutical manufacturing facilities

Key Construction Characteristics

100 µL holdup volume minimizes loss of valuable pharmaceutical compounds and biological materials, optimizing yield for medium-volume sterile processing applications
Polypropylene housing delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse bioprocessing conditions
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining aseptic transfer procedures in manufacturing environments
Integrated polypropylene prefilter extends membrane lifetime by capturing larger particulates upstream, reducing filter consumption in cell culture applications

Pharmaceutical and biotechnology laboratories processing medium-volume aqueous samples require sterilization technology that combines bacterial retention with immediate wettability and sterile handling. Hydrophilic PVDF syringe filters deliver 0.22 µm sterile-grade performance through naturally wettable membrane chemistry and aseptic packaging. Engineered to overcome your pharmaceutical processing challenges, this filtration solution provides processing confidence via immediate aqueous sample compatibility, validated microbial retention, and low protein binding for biopharmaceutical manufacturing, cell culture sterilization, and quality control applications requiring both efficient processing and bacterial elimination capabilities with contamination-free handling requirements.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.