Tisch
PVDF Syringe Filters, 0.22um, 33mm, Luer-Lok/Luer Slip, Sterile, 100 /Pk SKU: SF18230

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18230

Featuring hydrophilic PVDF membrane technology with sterile packaging engineered for bacterial retention in pharmaceutical and biotechnology workflows. The 0.22µm pore size delivers validated sterile-grade filtration while naturally wettable surface chemistry eliminates pre-treatment requirements for immediate aqueous sample processing. Integrated polypropylene prefilter extends operational life when filtering high-particulate biological samples. Robust polypropylene housing withstands pressures up to 87psi while maintaining thermal stability to 60°C for diverse bioprocessing conditions.

Key Hydrophilic PVDF Membrane Characteristics

• Naturally hydrophilic surface enables immediate aqueous filtration without alcohol pre-wetting, streamlining aseptic workflows
• 0.22µm pore size provides sterile-grade bacterial retention validated with Brevundimonas diminuta challenge testing
• Low protein binding preserves therapeutic proteins and enzymes during sterilization, minimizing product loss
• Broad chemical compatibility resists degradation from biological buffers, mild acids, and pharmaceutical formulations
• Sterile packaging eliminates contamination risks for aseptic processing, supporting GMP manufacturing requirements

Key Construction Characteristics

• Large 33mm diameter provides 4.9cm² filtration area supporting processing volumes exceeding 100ml capacity
• Low 100µL holdup volume minimizes sample retention, preserving valuable pharmaceutical formulations
• Integrated polypropylene prefilter extends membrane lifetime by capturing high particulate loads before sterile stage
• Dual Luer-Lok and Luer-Slip connections accommodate standard syringes, streamlining aseptic transfer procedures

SF18230 filters combine validated bacterial retention with rapid throughput for high-volume aqueous processing. The hydrophilic PVDF membrane delivers efficient flow rates through biological matrices while sterile packaging supports contamination-free handling. Built for pharmaceutical and biotechnology laboratories, this filtration solution provides reliable microbial elimination with low protein binding characteristics essential for therapeutic protein manufacturing and cell culture sterilization applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

43.51psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

33mm

Filtration Area

4.9cm²

Flow Rate

24.5ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Sterile

Volume Throughput (ml)

110ml

Weight

1.46

Wetability

Hydrophilic

• Culture Media Sterilization - Removes bacteria from aqueous culture media and biological supplements for mammalian cell bioprocessing workflows
• Buffer Sterilization - Sterilizes phosphate buffers and saline solutions for pharmaceutical manufacturing and aseptic laboratory research
• Protein Processing - Filters aqueous protein solutions while maintaining biological activity and concentration in biopharmaceutical operations
• Vaccine Manufacturing - Sterilizes aqueous vaccine formulations and biological buffers requiring validated bacterial elimination capabilities
• Water Quality Testing - Provides sterile aqueous samples for microbiological analysis in environmental monitoring and regulatory programs
• Culture Supplement Filtration - Sterilizes growth factors and serum additives for cell culture applications requiring contamination-free handling