Tisch
PVDF Syringe Filters, 0.22 um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF14456

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF14456

Precision 0.22 µm polyvinylidene fluoride membrane technology with integrated polypropylene prefilter delivers sterile-grade filtration performance for pharmaceutical manufacturing and microbiological testing applications requiring bacterial retention across organic and aqueous solvent systems. This configuration combines 4.08 cm² filtration area with 100 µL holdup volume and 25mm diameter design, enabling efficient processing of 10-100 ml sample volumes. Meanwhile, the hydrophobic membrane chemistry withstands aggressive chemical environments while maintaining low protein binding characteristics essential for biological sample sterilization and analytical workflows demanding both particulate removal and microbial control.

Key PVDF Membrane Characteristics

Hydrophobic surface requires alcohol or solvent pre-wetting before aqueous sample processing, making this membrane ideal for organic mobile phase sterilization and non-aqueous pharmaceutical formulations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, removing microorganisms including Brevundimonas diminuta for aseptic processing applications
Exceptional chemical resistance, stable operation across strong acids, bases, alcohols, and chlorinated solvents for diverse pharmaceutical and analytical chemistry applications
Low protein binding affinity maintains the concentration of therapeutic proteins and biomolecules during sterile filtration, minimizing product loss in biopharmaceutical manufacturing
Thermal stability up to 60°C with autoclave compatibility at 121°C enables filter sterilization for contamination-free processing in regulated manufacturing environments

Key Construction Characteristics

100 µL holdup volume preserves samples by reducing retention within the housing, maximizing recovery of valuable pharmaceutical compounds and analytical standards
Polypropylene housing construction provides reliable performance to 87 psi maximum operating pressure, delivering operational confidence for pressurized sterilization systems
Dual Luer-Lok and Luer-Slip connections integrate seamlessly with standard laboratory syringes without requiring adapters, streamlining aseptic transfer procedures
Integrated polypropylene prefilter captures coarse particulates upstream of the sterilizing membrane, extending filter lifetime in high-particulate sample applications

Pharmaceutical and microbiological laboratories processing medium-volume samples require sterilization technology that combines bacterial retention with chemical resistance and minimal protein loss. PVDF syringe filters deliver 0.22 µm sterile-grade performance through validated membrane technology and integrated prefilter protection. Built to support your critical sterilization workflows, this filtration solution provides performance reliability through proven microbial retention, broad solvent compatibility, and efficient sample processing for pharmaceutical manufacturing, quality control testing, and research applications demanding both particulate removal and bacterial elimination capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.