Tisch
PVDF Syringe Filters, 0.45um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF14457

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF14457

Precision PVDF membrane construction features a 0.45 µm pore rating and 25mm diameter. The 4.08 cm² filtration area provides efficient clarification of organic solvents for analytical chemistry. Pharmaceutical applications benefit from chemical-resistant filtration without sterile-grade particle retention. Users achieve high-throughput processing capabilities with the device. An integrated polypropylene prefilter extends operational life by capturing larger particles upstream. The hydrophobic membrane structure ensures optimal performance with non-polar solvents. Aqueous sample processing requires alcohol pre-wetting.

Key PVDF Membrane Characteristics

• Hydrophobic nature optimized for organic solvent processing, requiring pre-wetting with methanol or ethanol before transitioning to water-based samples
• Broad chemical compatibility resists degradation from aggressive solvents, acids, and bases with broad pH compatibility without membrane swelling or dissolution
• 0.45 µm pore rating removes particles and clarifies solutions for analytical procedures where bacterial removal is not required
• Low protein affinity maintains sample composition by minimizing biomolecule adsorption, essential for accurate protein quantification and enzymatic activity measurements
• Robust mechanical properties support pressures up to 87 psi, enabling rapid filtration of viscous samples and high-volume processing requirements

Key Construction Characteristics

• 100 µL holdup volume minimizes loss of expensive analytical samples and reagents by reducing retention within the filter assembly
• Polypropylene housing maintains structural integrity at operating temperatures up to 60°C and withstands both autoclave and gamma sterilization procedures
• Luer-Lok and Luer-Slip dual connections interface seamlessly with standard laboratory syringes without requiring specialty adapters or modified equipment
• 4.08 cm² filtration area with polypropylene prefilter configuration maximizes throughput capacity for medium-volume sample processing applications

Laboratories processing medium-volume organic samples require clarification technology combining chemical resistance with efficient particle removal. PVDF syringe filters deliver 0.45 µm clarification performance with broad solvent compatibility. Naturally hydrophobic membrane characteristics support challenging analytical workflows. Validated chemical resistance provides processing confidence for routine sample preparation. Applications requiring reliable clarification without bacterial retention benefit significantly.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

5.8psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophobic

• HPLC Sample Clarification - Removes particulates from organic mobile phases and sample extracts, protecting chromatography columns from fouling
• LC-MS Sample Preparation - Clarifies analytical samples in organic solvents before mass spectrometry analysis for accurate compound identification
• Organic Reagent Filtration - Processes chemical solutions and solvent mixtures for pharmaceutical manufacturing and research laboratory applications
• Environmental Extract Processing - Clarifies soil and water extracts in non-aqueous solvents before instrumental analysis for contaminant detection
• Polymer Solution Clarification - Removes particles from polymer solutions and resin preparations for materials science research and quality control
• Paint and Coating Analysis - Filters organic-based formulations for particle size analysis and quality assurance testing in manufacturing