Tisch
PVDF Syringe Filters, 0.22 um, 13mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF14460

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF14460

Featuring polyvinylidene fluoride membrane technology with 0.22 µm pore size, these 13mm filters deliver sterile-grade retention. They suit small-volume pharmaceutical applications requiring microbial control across organic solvent systems. The membrane enables reliable sterilization of 1-10 ml sample volumes through validated filtration performance. A compact design with 1.09 cm² filtration area and 10 µL holdup volume maximizes recovery. It ensures efficient sample conservation for chromatography preparation and quality control workflows.

Key PVDF Membrane Characteristics

• Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for sterile organic pharmaceutical formulations
• 0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination for pharmaceutical manufacturing
• Exceptional chemical resistance withstands aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across pharmaceutical workflows
• Naturally hydrophobic surface enables air and gas venting applications, efficiently displacing air from liquid handling systems where hydrophilic membranes would block gas passage
• Sterile packaging eliminates initial contamination risks for aseptic transfer procedures, supporting GMP compliance requirements in pharmaceutical production facilities

Key Construction Characteristics

• 10 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and analytical compounds
• Polypropylene housing provides structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C, ensuring reliable performance across laboratory conditions
• Dual Luer-Lok and Luer-Slip connections accommodate standard laboratory syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical workflows
• Integrated polypropylene prefilter with sterile packaging extends membrane lifetime while eliminating contamination risks for sensitive pharmaceutical sample processing

Pharmaceutical laboratories processing small-volume organic samples require sterilization technology combining bacterial retention with chemical resistance. PVDF syringe filters deliver 0.22 µm sterile-grade performance with broad solvent compatibility and aseptic packaging. The membrane provides operational excellence through proven microbial retention and minimal holdup. Validated chemical stability supports chromatography preparation and manufacturing applications requiring efficient processing.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

14.5psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

13mm

Filtration Area

1.09cm²

Flow Rate

5ml

Holdup Volume

10μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Sterile

Volume Throughput (ml)

10ml

Weight

0.40

Wetability

Hydrophobic

• Sterile HPLC Mobile Phases - Removes bacteria from organic and aqueous chromatography solvents for pharmaceutical analytical testing
• Pharma Formulation Sterilization - Sterilizes drug solutions in organic solvents for small-batch production and development applications
• Analytical Standard Sterilization - Provides sterile reference materials and calibration solutions for validated pharmaceutical analytical methods
• LC-MS Sample Preparation - Sterilizes analytical samples in organic solvents before mass spectrometry for pharmaceutical compound identification
• Organic Reagent Sterilization - Processes chemical solutions requiring microbial control in pharmaceutical manufacturing and research applications
• Microbiological Sample Processing - Prepares sterile samples for microbial limit testing and bioburden analysis in regulatory compliance programs