Tisch
PVDF Syringe Filters, 0.22 um, 25mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF14462

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF14462

Precision 0.22 µm polyvinylidene fluoride membrane technology with sterile packaging and integrated polypropylene prefilter delivers validated bacterial retention for pharmaceutical manufacturing applications requiring aseptic processing of organic solvents, aggressive chemical formulations, and mixed-phase samples across drug development and quality control workflows. This configuration combines 4.08 cm² filtration area with 100 µL holdup volume and hydrophobic surface chemistry, enabling reliable sterilization of 10-100 ml sample volumes while maintaining low protein binding characteristics essential for therapeutic protein processing. Meanwhile, the 25mm diameter design with dual luer connections provides versatile integration into pharmaceutical manufacturing equipment and laboratory workflows demanding both microbial control and chemical resistance for sterile filtration applications.

Key PVDF Membrane Characteristics

Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, making this membrane ideal for sterile organic pharmaceutical formulations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination for aseptic pharmaceutical manufacturing
Exceptional chemical resistance withstands aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across pharmaceutical development workflows
Low protein binding affinity maintains concentration of therapeutic proteins during sterile filtration, minimizing adsorption losses in biopharmaceutical manufacturing applications
Sterile packaging eliminates contamination risks for aseptic transfer procedures, supporting GMP compliance requirements in pharmaceutical production environments

Key Construction Characteristics

100 µL holdup volume preserves samples by reducing retention within the housing, maximizing recovery of valuable pharmaceutical compounds and analytical standards
Polypropylene housing construction delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse manufacturing conditions
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical processing workflows
Integrated polypropylene prefilter extends membrane lifetime by capturing coarse particulates upstream, reducing filter consumption in pharmaceutical sample applications

Pharmaceutical laboratories processing medium-volume organic samples require sterilization technology that combines bacterial retention with chemical resistance and sterile packaging. PVDF syringe filters deliver 0.22 µm sterile-grade performance through hydrophobic membrane chemistry and integrated prefilter protection. Built to support your critical pharmaceutical workflows, this filtration solution provides performance reliability through validated microbial retention, broad solvent compatibility, and low protein binding for drug manufacturing, analytical testing, and quality control applications demanding both efficient processing and bacterial elimination capabilities with aseptic handling requirements.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.