Tisch
PVDF Syringe Filters, 0.45um, 25mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF14463

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF14463

Precision 0.45 µm polyvinylidene fluoride membrane technology features sterile packaging and an integrated polypropylene prefilter. It delivers clarification performance for pharmaceutical applications requiring particulate removal and chemical resistance. The design suits organic solvent systems and aggressive chemical environments in analytical testing. A 4.08 cm² filtration area combines with a rapid 32 ml/min flow rate. The 25mm diameter enables efficient processing of 10-100 ml sample volumes. Meanwhile, the hydrophobic surface chemistry provides exceptional chemical resistance. Sterile packaging eliminates initial contamination risks for pharmaceutical manufacturing workflows.

Key PVDF Membrane Characteristics

• Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for organic pharmaceutical clarification
• 0.45 µm pore size removes particulates from analytical samples for chromatography workflows, protecting downstream instrumentation without providing sterile-grade filtration
• Exceptional chemical resistance ensures stable operation with aggressive organic solvents, including chlorinated compounds, ketones, esters, and aromatic hydrocarbons
• Naturally hydrophobic surface enables air and gas venting applications, efficiently displacing air from liquid handling systems where hydrophilic membranes would block gas passage
• Rapid throughput with a 32ml/min flow rate reduces processing time for medium-volume samples, improving workflow efficiency in analytical laboratories

Key Construction Characteristics

• 100 µL holdup volume minimizes loss of valuable pharmaceutical compounds and analytical standards, maximizing recovery for medium-volume clarification applications
• Polypropylene housing construction provides structural integrity to 87 psi maximum operating pressure, delivering reliable performance for pressurized filtration systems
• Dual Luer-Lok and Luer-Slip connections integrate seamlessly with standard laboratory syringes without adapters, streamlining workflow integration in pharmaceutical testing
• Integrated polypropylene prefilter with sterile packaging extends membrane lifetime while eliminating contamination risks for sensitive pharmaceutical sample processing

Pharmaceutical laboratories processing medium-volume organic samples require clarification technology combining chemical resistance with sterile handling. PVDF syringe filters deliver 0.45 µm clarification performance through hydrophobic membrane chemistry. The solution supports your critical pharmaceutical workflows through validated chemical stability. Rapid throughput characteristics improve lab efficiency. Sterile packaging supports chromatography preparation and quality control applications requiring reliable particulate removal.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

5.8psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Weight

0.88

Wetability

Hydrophobic

• HPLC Mobile Phase Clarification - Removes particles from organic and aqueous chromatography solvents for pharmaceutical analytical testing
• LC-MS Sample Preparation - Clarifies analytical extracts in organic solvents before mass spectrometry for pharmaceutical compound identification
• Pharmaceutical QC Testing - Filters drug formulations and organic extracts for chromatographic analysis in quality control laboratories
• Environmental Extract Analysis - Clarifies soil and water extracts in non-aqueous solvents for contaminant detection in regulatory testing
• Organic Reagent Filtration - Processes chemical solutions and analytical standards for pharmaceutical manufacturing quality assurance applications
• Polymer Solution Processing - Removes particulates from resin solutions and coating formulations for materials science research applications