Tisch
PVDF Syringe Filters, 0.22 um, 17mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF15614

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF15614

Featuring polyvinylidene fluoride membrane technology with 0.22 µm pore size and integrated polypropylene prefilter, these 17mm diameter filters deliver sterile-grade bacterial retention for pharmaceutical and analytical applications requiring microbial control across organic solvent systems and aggressive chemical environments without compromising low protein binding characteristics. This combination enables reliable sterilization of small-volume samples through validated filtration performance. Meanwhile, the compact design with 1.65 cm² filtration area and 20 µL holdup volume maximizes recovery of valuable pharmaceutical compounds and analytical standards for chromatography preparation and quality control workflows processing volumes between 1-20 ml.

Key PVDF Membrane Characteristics

Hydrophobic surface chemistry requires pre-wetting with alcohols or compatible organic solvents before aqueous sample processing, optimizing performance for sterile HPLC mobile phases
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial control for pharmaceutical manufacturing applications
Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across analytical workflows
Low protein binding affinity preserves therapeutic protein concentration during sterile filtration, minimizing product loss in biopharmaceutical development and manufacturing processes
Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for aseptic pharmaceutical and research laboratory applications

Key Construction Characteristics

20 µL holdup volume preserves samples by minimizing retention within the filter housing, maximizing recovery for small-volume sterile pharmaceutical formulations and analytical compounds
Polypropylene housing provides structural integrity to 87 psi burst pressure with thermal stability to 60°C, ensuring operational confidence across pressurized sterilization systems
Dual Luer-Lok and Luer-Slip connections accommodate standard laboratory syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical manufacturing environments
Integrated polypropylene prefilter captures coarse particulates upstream of the sterilizing membrane, extending filter lifetime in high-particulate pharmaceutical sample applications

Pharmaceutical and analytical laboratories processing small-volume organic samples require sterilization technology that combines bacterial retention with chemical resistance and minimal holdup. PVDF syringe filters deliver 0.22 µm sterile-grade performance with broad solvent compatibility and low protein binding. Designed for your most demanding pharmaceutical workflows, this membrane technology provides operational excellence through proven microbial retention, validated chemical stability, and compact design for sample conservation in chromatography preparation, quality control testing, and manufacturing applications requiring both particulate removal and bacterial elimination capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.