Tisch
PVDF Syringe Filters, 0.22 um, 17mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF15614

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF15614

Featuring polyvinylidene fluoride membrane technology with 0.22 µm pore size and an integrated polypropylene prefilter, these 17mm diameter filters deliver sterile-grade bacterial retention. They serve pharmaceutical applications requiring microbial control across organic solvent systems. The filters withstand aggressive chemical environments without compromising performance. A compact design with 1.65 cm² filtration area and 20 µL holdup volume maximizes recovery. It handles volumes between 1-20 ml effectively for chromatography preparation and quality control workflows.

Key PVDF Membrane Characteristics

• Hydrophobic surface chemistry requires pre-wetting with alcohols or compatible organic solvents before aqueous sample processing, optimizing performance for sterile HPLC mobile phases
• 0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial control for pharmaceutical manufacturing applications
• Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across analytical workflows
• Naturally hydrophobic surface enables air and gas venting applications, efficiently displacing air from liquid handling systems where hydrophilic membranes would block gas passage
• Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for aseptic pharmaceutical and research laboratory applications

Key Construction Characteristics

• 20 µL holdup volume preserves samples by minimizing retention within the filter housing, maximizing recovery for small-volume pharmaceutical formulations and analytical compounds
• Polypropylene housing provides structural integrity to 87 psi burst pressure with thermal stability to 60°C, ensuring operational confidence across pressurized sterilization systems
• Dual Luer-Lok and Luer-Slip connections accommodate standard laboratory syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical manufacturing environments
• Integrated polypropylene prefilter captures coarse particulates upstream of the sterilizing membrane, extending filter lifetime in high-particulate pharmaceutical sample applications

Pharmaceutical and analytical laboratories processing small-volume organic samples require sterilization technology. It must combine bacterial retention with chemical resistance and minimal holdup. PVDF syringe filters deliver 0.22 µm sterile-grade performance with broad solvent compatibility. Designed for your most demanding pharmaceutical workflows, the membrane technology provides operational excellence. Proven microbial retention and validated chemical stability support chromatography preparation. Users achieve efficient sample conservation in quality control testing.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

14.5psi

Burst Pressure (psi)

87psi.

Connection Type

Luer-Lok/Luer Slip

Construction

Polypropylene (PP)

Diameter

17mm

Filtration Area

1.65cm²

Flow Rate

8ml

Holdup Volume

20μL

Incompatibility

Bases, esters, ethers, ketones, aqueous samples without rewetting

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

20ml

Weight

0.33

Wetability

Hydrophobic

• HPLC Mobile Phase Sterilization - Removes bacteria from organic and aqueous chromatography solvents for pharmaceutical quality control testing
• Pharmaceutical Sterilization - Sterilizes drug solutions and parenteral formulations in organic solvents for small-batch production applications
• Analytical Standard Sterilization - Provides sterile reference standards and calibration solutions for validated analytical methods in laboratories
• LC-MS Sample Preparation - Sterilizes analytical samples in organic solvents before mass spectrometry analysis for compound identification
• Organic Reagent Sterilization - Processes chemical solutions and solvent mixtures requiring microbial control in pharmaceutical manufacturing
• Microbiological Sample Processing - Prepares sterile analytical samples for microbial limit testing and bioburden analysis in regulatory programs