Tisch
PVDF Syringe Filters, 0.22 um, 4mm, Luer-Lok/Luer Slip, Nonsterile, 200/Pk SKU: SF17510

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17510

Precision 0.22 µm polyvinylidene fluoride membrane technology with integrated polypropylene prefilter and ultra-low 1 µL holdup volume delivers sterile-grade bacterial retention for micro-volume pharmaceutical and analytical applications requiring maximum recovery of precious samples across organic solvent systems and aggressive chemical environments. This configuration combines 0.125 cm² filtration area with 4mm diameter design specifically engineered for volumes less than 1 ml, enabling sterilization of expensive analytical standards, rare biological compounds, and limited-availability research materials. Meanwhile, the hydrophobic surface chemistry provides exceptional chemical resistance while maintaining low protein binding characteristics essential for therapeutic protein processing and pharmaceutical quality control workflows demanding both microbial elimination and sample conservation.

Key PVDF Membrane Characteristics

Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for micro-volume sterile HPLC preparations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial control for pharmaceutical applications
Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across analytical workflows
Low protein binding affinity preserves therapeutic protein concentration during sterile filtration, minimizing adsorption losses critical for micro-volume pharmaceutical samples
Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for aseptic micro-volume pharmaceutical processing

Key Construction Characteristics

1 µL holdup volume maximizes recovery by minimizing sample retention, absolutely critical for preserving expensive analytical standards and rare research compounds
Polypropylene housing provides structural integrity to 87 psi maximum operating pressure, ensuring operational confidence for micro-volume pressurized sterilization
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical workflows
Integrated polypropylene prefilter extends membrane lifetime by capturing coarse particulates upstream, protecting the sterilizing membrane in micro-volume applications

Pharmaceutical and analytical laboratories processing micro-volume precious samples require sterilization technology that combines bacterial retention with minimal holdup and broad solvent compatibility. PVDF syringe filters deliver 0.22 µm sterile-grade performance through hydrophobic membrane chemistry and ultra-low holdup design. Built to support your critical micro-volume workflows, this filtration solution provides performance reliability through proven microbial retention, minimal 1 µL holdup for maximum recovery, and validated chemical stability for pharmaceutical development, analytical testing, and research applications demanding both bacterial elimination and sample conservation capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.