Tisch
PVDF Syringe Filters, 0.22 um, 4mm, Luer-Lok/Luer Slip, Nonsterile, 200/Pk SKU: SF17510

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17510

Precision 0.22 µm polyvinylidene fluoride membrane technology features an integrated polypropylene prefilter. It delivers sterile-grade retention for micro-volume applications. The ultra-low 1 µL holdup volume maximizes recovery of precious samples. Users can safely process organic solvent systems and aggressive chemical environments. A 0.125 cm² filtration area combines with a 4mm diameter design. Specifically engineered for volumes less than 1 ml, the filter enables sterilization of expensive analytical standards. Rare biological compounds and limited-availability research materials benefit from the design. Meanwhile, the hydrophobic surface chemistry provides exceptional chemical resistance. It maintains compatibility with aggressive solvents essential for pharmaceutical quality control workflows.

Key PVDF Membrane Characteristics

Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for micro-volume sterile HPLC preparations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial control for pharmaceutical applications
Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons
Naturally hydrophobic surface enables air and gas venting applications, efficiently displacing air from micro-volume liquid handling systems where hydrophilic membranes would block gas passage
Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for aseptic micro-volume pharmaceutical processing

Key Construction Characteristics

1 µL holdup volume maximizes recovery by minimizing sample retention, absolutely critical for preserving expensive analytical standards and rare research compounds
Polypropylene housing provides structural integrity to 87 psi maximum operating pressure, ensuring operational confidence for micro-volume pressurized sterilization
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical workflows
Integrated polypropylene prefilter extends membrane lifetime by capturing coarse particulates upstream, protecting the sterilizing membrane in micro-volume applications

Pharmaceutical laboratories processing micro-volume precious samples require specific sterilization technology. It must combine bacterial retention with minimal holdup and broad solvent compatibility. PVDF syringe filters deliver 0.22 µm sterile-grade performance through hydrophobic membrane chemistry. The ultra-low holdup design maximizes yield. Built to support critical micro-volume workflows, the solution provides performance reliability. Users benefit from proven microbial retention and minimal 1 µL holdup. Validated chemical stability supports pharmaceutical development and analytical testing.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.