Tisch
PVDF Syringe Filters, 0.45um, 4mm, Luer-Lok/Luer Slip, Nonsterile, 200/Pk SKU: SF17511

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF17511

Precision 0.45 µm polyvinylidene fluoride membrane technology features an ultra-low 1 µL holdup volume. An integrated polypropylene prefilter delivers clarification performance for micro-volume analytical applications. The design ensures maximum recovery of precious samples and chemical resistance. Users efficiently remove particulates across organic solvent systems and aggressive chemical environments. A compact 0.125 cm² filtration area combines with a 4mm diameter design. Specifically engineered for volumes less than 1 ml, the filter enables reliable clarification. Hydrophobic surface chemistry provides exceptional chemical resistance. It minimizes sample loss for chromatography preparation and quality control workflows.

Key PVDF Membrane Characteristics

• Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for micro-volume organic sample clarification
• 0.45 µm pore size removes particulates from analytical samples for chromatography workflows, protecting downstream instrumentation without providing sterile-grade filtration
• Exceptional chemical resistance ensures stable operation with aggressive organic solvents, including chlorinated compounds, ketones, esters, and aromatic hydrocarbons
• Naturally hydrophobic surface enables air and gas venting applications, efficiently displacing air from micro-volume liquid handling systems where hydrophilic membranes would block gas passage
• Autoclave compatibility at 121°C with gamma sterilization capability provides contamination control options for sensitive analytical laboratory applications

Key Construction Characteristics

• 1 µL holdup volume maximizes recovery by minimizing sample retention, absolutely critical for preserving expensive analytical standards and rare research compounds
• Polypropylene housing provides structural integrity to 87 psi maximum operating pressure, ensuring operational confidence for micro-volume clarification applications
• Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining workflow integration in pharmaceutical testing environments
• Integrated polypropylene prefilter extends membrane lifetime by capturing coarse particulates upstream, protecting the primary membrane in micro-volume applications

Analytical laboratories processing micro-volume organic solvent samples require specific clarification technology. It must combine minimal holdup with broad chemical resistance. PVDF syringe filters deliver 0.45 µm clarification performance through hydrophobic membrane chemistry. The ultra-low holdup design maximizes yield. Built to support critical micro-volume workflows, the filtration solution provides performance reliability. Users benefit from minimal 1 µL holdup volume and validated chemical stability. Naturally hydrophobic surface characteristics support HPLC mobile phase preparation.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

5.8psi

Connection Type

Luer-Lok/Luer Slip

Diameter

4mm

Filtration Area

0.125cm²

Flow Rate

1ml

Holdup Volume

1μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

200

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

1ml

Weight

0.24

Wetability

Hydrophobic

• Analytical Standard Clarification - Removes particulates from reference materials and calibration solutions for pharmaceutical analytical methods
• Micro-Volume HPLC Preparation - Clarifies precious organic mobile phases and analytical samples for high-value chromatography applications
• Rare Compound Processing - Filters limited-availability pharmaceutical compounds requiring maximum sample recovery with efficient clarification
• NMR Sample Preparation - Clarifies micro-volume samples for nuclear magnetic resonance spectroscopy in pharmaceutical structure elucidation
• Mass Spectrometry Sample Prep - Removes particulates from expensive analytical samples in organic solvents before mass spectrometry analysis
• Pharmaceutical QC Testing - Processes micro-volume pharmaceutical samples for clarification in quality control laboratories