Tisch
PVDF Syringe Filters, 0.1um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF18032

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18032

Biopharmaceutical and microbiological laboratories demand ultrafiltration technology capable of removing mycoplasma and submicron contaminants from critical pharmaceutical formulations while maintaining compatibility with organic solvents and aggressive chemical environments encountered in drug manufacturing processes. Advanced polyvinylidene fluoride membrane technology with 0.1 µm pore size delivers mycoplasma removal capability through ultrafine filtration performance that exceeds standard sterile-grade specifications while preserving low protein binding characteristics essential for biological sample processing. Furthermore, the 25mm diameter configuration with 4.08 cm² filtration area enables efficient processing of 10-100 ml sample volumes, making this design ideal for pharmaceutical development and quality control applications requiring submicron particle removal and microbial control beyond conventional sterile filtration capabilities.

Key PVDF Membrane Characteristics

Hydrophobic surface chemistry requires pre-wetting with alcohols or compatible solvents before aqueous processing, optimizing performance for organic pharmaceutical formulations
0.1 µm pore size removes mycoplasma and submicron particles, providing critical filtration for cell culture applications and pharmaceutical manufacturing requiring ultrafine contamination control
Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, and aromatic hydrocarbons across pharmaceutical workflows
Low protein binding affinity preserves therapeutic protein concentration during ultrafiltration, minimizing product loss in biopharmaceutical development and manufacturing applications
Thermal stability to 60°C with autoclave capability at 121°C provides sterilization options for contamination-free processing in regulated pharmaceutical environments

Key Construction Characteristics

100 µL holdup volume minimizes loss of valuable pharmaceutical compounds and biological materials, optimizing yield for medium-volume sample processing applications
Polypropylene housing delivers structural integrity to 87 psi maximum operating pressure with gamma sterilization compatibility for aseptic manufacturing environments
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining integration into pharmaceutical processing and analytical workflows
Integrated polypropylene prefilter extends membrane lifetime by capturing larger particulates upstream, reducing filter consumption in high-particulate pharmaceutical sample

Pharmaceutical and biotechnology laboratories processing critical biological samples require ultrafiltration technology that combines mycoplasma removal with chemical resistance and minimal protein loss. PVDF syringe filters deliver 0.1 µm ultrafiltration performance through hydrophobic membrane chemistry and integrated prefilter design. Optimized for your challenging pharmaceutical workflows, this filtration solution provides workflow efficiency with validated mycoplasma retention, broad solvent compatibility, and low protein binding for biopharmaceutical manufacturing, cell culture processing, and quality control applications requiring submicron particle removal beyond conventional sterile-grade specifications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.