Tisch
PVDF Syringe Filters, 0.1um, 25mm, Luer-Lok/Luer Slip, Nonsterile, 100/Pk SKU: SF18032

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18032

Biopharmaceutical laboratories demand ultrafiltration technology capable of removing mycoplasma and submicron contaminants. Critical pharmaceutical formulations require compatibility with organic solvents and aggressive chemical environments. Advanced polyvinylidene fluoride membrane technology with 0.1 µm pore size delivers mycoplasma removal capability. Ultrafine filtration performance exceeds standard sterile-grade specifications. A 25mm diameter configuration with 4.08 cm² filtration area enables efficient processing of 10-100 ml volumes. The design suits pharmaceutical development and quality control applications requiring submicron microbial control.

Key PVDF Membrane Characteristics

• Hydrophobic surface chemistry requires pre-wetting with alcohols or compatible solvents before aqueous processing, optimizing performance for organic pharmaceutical formulations
• 0.1 µm pore size removes mycoplasma and submicron particles, providing critical filtration for cell culture applications and pharmaceutical manufacturing requiring ultrafine contamination control
• Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, and aromatic hydrocarbons across pharmaceutical workflows
• Naturally hydrophobic structure functions as a superior barrier to aqueous liquids and aerosols, making it ideal for protecting equipment from viral and bacterial ingress
• Thermal stability to 60°C with autoclave capability at 121°C provides sterilization options for contamination-free processing in regulated pharmaceutical environments

Key Construction Characteristics

• 100 µL holdup volume minimizes loss of valuable pharmaceutical compounds and biological materials, optimizing yield for medium-volume sample processing applications
• Polypropylene housing delivers structural integrity to 87 psi maximum operating pressure with gamma sterilization compatibility for aseptic manufacturing environments
• Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining integration into pharmaceutical processing and analytical workflows
• Integrated polypropylene prefilter extends membrane lifetime by capturing larger particulates upstream, reducing filter consumption in high-particulate pharmaceutical samples

Laboratories processing critical samples require ultrafiltration technology. It must combine mycoplasma removal with chemical resistance. PVDF syringe filters deliver 0.1 µm ultrafiltration performance through hydrophobic membrane chemistry. The solution provides workflow efficiency with validated mycoplasma retention and broad solvent compatibility. Biopharmaceutical manufacturing and quality control applications benefit from submicron particle removal capabilities.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

26.1psi

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

8ml

Holdup Volume

100μL

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

100-130μm

Pack Count

100

Pore Size (µm)

0.1

Prefilter (Yes/No)

Yes

Prefilter Material

PP

Sterility

Nonsterile

Sterilization

Autoclave at 121°C for 30min/ gamma 25kGy

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophobic

• Mycoplasma Removal - Eliminates mycoplasma contamination from cell culture media and biological buffers for biopharmaceutical manufacturing
• Culture Media Sterilization - Provides ultrafine filtration for serum supplements and growth factors requiring submicron contamination control
• Pharmaceutical Formulation Processing - Filters drug solutions and parenteral formulations requiring mycoplasma removal in pharmaceutical production
• Virus Removal Studies - Supports viral clearance validation studies in biopharmaceutical development requiring submicron filtration performance
• Nanoparticle Clarification - Processes pharmaceutical nanoformulations requiring ultrafine particle removal without compromising product integrity
• Biotechnology QC Testing - Filters biological samples for mycoplasma testing and contamination analysis in pharmaceutical quality control labs