Tisch
PVDF Syringe Filters, 0.22um, 33mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF18221

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18221

Precision 0.22 µm polyvinylidene fluoride membrane technology with sterile packaging and integrated polypropylene prefilter delivers validated bacterial retention for high-volume pharmaceutical applications requiring microbial control, chemical resistance, and contamination-free aseptic processing across organic solvent systems and mixed-phase samples encountered in pharmaceutical manufacturing and analytical testing workflows. This configuration combines 4.9 cm² filtration area with 100 µL holdup volume and 33mm diameter design specifically engineered for volumes exceeding 100 ml, enabling reliable sterilization while maintaining low protein binding characteristics essential for therapeutic protein processing. Meanwhile, the hydrophobic surface chemistry provides exceptional chemical resistance while sterile packaging eliminates initial contamination risks for pharmaceutical manufacturing and quality control applications demanding both bacterial elimination and efficient sample processing with aseptic handling requirements.

Key PVDF Membrane Characteristics

Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for sterile organic pharmaceutical formulations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination for pharmaceutical manufacturing
Exceptional chemical resistance maintains compatibility with aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across workflows
Low protein binding characteristics maintain the concentration of therapeutic proteins during sterile filtration, minimizing product loss in biopharmaceutical applications
Sterile packaging eliminates initial contamination risks for aseptic transfer procedures, supporting GMP compliance requirements in pharmaceutical production facilities

Key Construction Characteristics

100 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and biological materials
Polypropylene housing construction delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C for diverse manufacturing conditions
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical workflows
Integrated polypropylene prefilter with sterile packaging extends membrane lifetime while eliminating contamination risks for high-volume pharmaceutical processing

Pharmaceutical laboratories processing high-volume organic samples require sterilization technology that combines bacterial retention with chemical resistance and sterile handling. PVDF syringe filters deliver 0.22 µm sterile-grade performance through hydrophobic membrane chemistry and aseptic packaging. Built to support your critical pharmaceutical workflows, this filtration solution provides performance reliability through proven microbial retention, large filtration area for high-volume efficiency, and validated chemical stability for chromatography preparation, quality control testing, and manufacturing applications requiring both efficient processing and bacterial elimination capabilities with contamination-free handling requirements.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.