Tisch
PVDF Syringe Filters, 0.22um, 33mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF18221

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18221

Sterile filtration of aggressive organic solvents requires a robust membrane capable of withstanding harsh chemical conditions. Hydrophobic PVDF syringe filters with a 0.22 µm pore size deliver validated sterility for these demanding pharmaceutical applications. The 33mm diameter housing incorporates a polypropylene prefilter to handle volumes exceeding 100 mL without premature clogging. Operators must pre-wet the membrane with alcohol before processing aqueous solutions, although it excels primarily with organic fluids. Rigorous sterility testing ensures that every filter unit prevents microbial ingress during critical aseptic transfers.

Key PVDF Membrane Characteristics

Hydrophobic surface chemistry requires pre-wetting with alcohols before aqueous processing, but allows direct filtration of organic solvents
Validated 0.22 µm pore size provides sterile-grade retention to ensure microbial elimination for critical pharmaceutical manufacturing workflows
Exceptional chemical resistance enables the safe filtration of aggressive solvents, including chlorinated compounds, ketones, and aromatic hydrocarbons
High structural integrity preserves membrane performance under pressure, making it ideal for the sterile venting of bioreactors and carboys
Sterile packaging ensures immediate readiness for aseptic processes, eliminating the need for autoclaving before use in cleanrooms

Key Construction Characteristics

Optimized 100 µL holdup volume maximizes yield by reducing sample retention within the housing for valuable formulations
Polypropylene housing construction delivers structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C
Dual Luer-Lok and Luer-Slip connections accommodate standard syringes without adapters to streamline aseptic transfer procedures
An integrated polypropylene prefilter protects the final membrane from fouling to extend life when processing particulate-laden fluids

Maintain the integrity of your aseptic workflows by choosing a filter designed for chemical resistance and high throughput. You can confidently sterilize larger batches of organic solvents thanks to the expanded 4.9 cm² filtration area. The integrated prefilter significantly extends functional life by capturing gross particulates upstream of the main membrane. Validated sterile packaging allows for immediate use in controlled environments without additional preparation steps. Rely on this durable solution to protect your sensitive instrumentation and biological cultures from microbial contamination.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.