Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18223
Pharmaceutical manufacturing and biotechnology research facilities demand sterile filtration capability that combines absolute bacterial retention with chemical resistance spanning organic solvents, aggressive acids, and challenging mobile phases where traditional hydrophilic membranes fail under harsh analytical conditions. Precision 0.22 µm hydrophobic PVDF membrane engineering delivers this capability. Furthermore, the 17mm compact diameter with gamma-sterilized packaging provides immediate deployment in critical sterile workflows requiring organic solvent compatibility and contamination-free processing assurance.
Key PVDF Membrane Characteristics
- Hydrophobic Membrane Architecture - Enables exceptional performance with organic solvents and non-aqueous solutions following alcohol pre-wetting protocols
- Broad Chemical Compatibility Spectrum - Stable operation across alcohols, ketones, hydrocarbons, and acids, maintaining membrane integrity throughout aggressive applications
- 0.22 µm Absolute Bacterial Retention - Ensures sterile filtration performance, removing bacteria and particles, protecting product quality in pharmaceutical manufacturing
- Minimal Biomolecule Adsorption - Preserves protein concentration and sample composition through low-binding surface chemistry critical for biological preparations
- Outstanding Chemical Stability - Maintains compatibility across extreme pH ranges and concentrated chemical exposures, delivering consistent sterile filtration reliability
Key Construction Characteristics
- 20 µL Minimal Holdup Design - Optimizes yield for small-volume applications, maximizing recovery of valuable analytical specimens and research preparations
- Polypropylene Housing with 100°C Rating - Delivers reliable thermal performance and chemical resistance across demanding sterilization protocols and high-temperature processing
- Dual Luer-Lok/Luer Slip Connection - Supports versatile syringe attachment options, ensuring secure, leak-free operation across diverse laboratory instrumentation configurations
- 1.65 cm² Filtration Area - Provides efficient processing through optimized membrane surface supporting 9 ml/min flow rates at 10 psi operating pressure
Engineered to overcome your challenging sterile filtration requirements where organic solvent compatibility and absolute bacterial retention cannot compromise processing efficiency or analytical precision. The hydrophobic PVDF membrane resists chemical degradation while gamma-sterilized construction ensures contamination-free handling. Your laboratory achieves processing confidence via validated 0.22 µm sterile filtration, exceptional chemical resistance spanning acids and organic mobile phases, and optimized 20 µL holdup design minimizing sample volume requirements across pharmaceutical development, chromatography, and biotechnology applications.
For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 0.1psi.
- Burst Pressure (psi)
- 87psi.
- Connection Type
- Luer-Lok/Luer Slip
- Construction
- Polypropylene (PP)
- Diameter
- 17mm
- Filtration Area
- 1.65cm²
- Flow Rate
- 9ml/ min @ 10psi.
- Holdup Volume
- 20µl
- Incompatibility
- Bases, esters, ethers, ketones, aqueous samples without rewetting
- Material
- Polyvinylidene Fluoride (PVDF)
- Maximum Operating Temperature (°C)
- 100°C
- Pore Size (µm)
- 0.22
- Sterility
- Sterile
- Volume Throughput (ml)
- 20ml
- Wetability
- Hydrophobic
- HPLC Mobile Phase Sterilization - Removes bacteria from organic mobile phases, protecting analytical columns and chromatography system integrity
- Pharmaceutical Injectable Preparation - Provides sterile filtration for small-batch drug formulations, ensuring patient safety and regulatory compliance
- Organic Solvent Sample Sterilization - Processes aggressive chemicals for sterile analysis, maintaining chemical stability and microbial control
- API Solution Sterilization - Filters active pharmaceutical ingredients dissolved in organic solvents, ensuring sterile processing conditions
- Analytical Standard Preparation - Sterilizes reference solutions and calibration standards, preventing microbial interference in analytical testing
- Research Sample Sterilization - Processes small-volume biological and chemical samples requiring absolute bacterial retention and solvent compatibility