Tisch
PVDF Syringe Filters, 0.22um, 30mm, Luer-Lok/Luer Slip, Sterile, 100/Pk SKU: SF18224

Polyvinylidene Fluoride (PVDF) Syringe Filters - SF18224

Featuring polyvinylidene fluoride membrane technology with 0.22 µm pore size, sterile packaging, and integrated polypropylene prefilter, these 30mm diameter filters deliver sterile-grade bacterial retention for high-volume pharmaceutical and analytical applications requiring microbial control, chemical resistance, and contamination-free aseptic processing across organic solvent systems and mixed-phase samples. This membrane enables reliable sterilization of volumes exceeding 100 ml through validated filtration performance while maintaining low protein binding characteristics essential for therapeutic protein processing and pharmaceutical manufacturing. Meanwhile, the design with 4.9 cm² filtration area and 100 µL holdup volume maximizes recovery of valuable pharmaceutical compounds and biological materials for quality control and manufacturing applications requiring both efficient sample conservation and bacterial elimination with sterile handling capabilities.

Key PVDF Membrane Characteristics

Hydrophobic surface requires pre-wetting with alcohols or compatible organic solvents before aqueous processing, optimizing performance for sterile organic pharmaceutical formulations
0.22 µm pore size provides sterile-grade filtration with validated bacterial retention, including Brevundimonas diminuta, ensuring microbial elimination for pharmaceutical manufacturing
Exceptional chemical resistance withstands aggressive organic solvents, including chlorinated compounds, alcohols, ketones, and aromatic hydrocarbons across pharmaceutical workflows
Low protein binding affinity preserves therapeutic protein concentration during sterile filtration, minimizing product loss in biopharmaceutical development and manufacturing
Sterile packaging eliminates initial contamination risks for aseptic transfer procedures, supporting GMP compliance requirements in pharmaceutical production facilities

Key Construction Characteristics

100 µL holdup volume optimizes yield by reducing sample retention within the housing, preserving valuable pharmaceutical formulations and biological materials
Polypropylene housing provides structural integrity to 87 psi maximum operating pressure with thermal stability to 60°C, ensuring reliable performance across laboratory conditions
Dual Luer-Lok and Luer-Slip connections accommodate standard laboratory syringes without adapters, streamlining aseptic transfer procedures in pharmaceutical workflows
Integrated polypropylene prefilter with sterile packaging extends membrane lifetime while eliminating contamination risks for high-volume pharmaceutical sample processing

Pharmaceutical laboratories processing high-volume organic samples require sterilization technology that combines bacterial retention with chemical resistance and sterile handling. PVDF syringe filters deliver 0.22 µm sterile-grade performance with broad solvent compatibility and aseptic packaging. Designed for your most demanding pharmaceutical workflows, this membrane technology provides operational excellence through proven microbial retention, large filtration area for high-volume efficiency, and validated chemical stability for chromatography preparation, quality control testing, and manufacturing applications requiring both efficient processing and bacterial elimination capabilities with contamination-free handling requirements.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.