Tisch
PVDF Syringe Filters, 0.45um, 25mm, Double Luer Lock, PP Housing, Nonsterile, 100/Pk SKU: SPEC18208

Polyvinylidene Fluoride (PVDF) Syringe Filters - SPEC18208

Analytical chemistry and pharmaceutical laboratories demand clarification solutions for organic solvent-based samples where hydrophilic membranes degrade and compromise both sample integrity and analytical accuracy in critical applications. Hydrophobic 0.45µm PVDF membrane technology delivers exceptional chemical resistance. Double Luer Lock construction with validated 116psi burst pressure, 80°C temperature stability, and polypropylene housing provides the mechanical integrity your workflows require when processing chemically demanding samples.

Key PVDF Membrane Characteristics

• Hydrophobic 0.45µm PVDF membrane requires alcohol pre-wetting before aqueous samples but enables specialized air venting capabilities and aggressive solvent clarification impossible with hydrophilic materials
• Exceptional chemical compatibility resists degradation from alcohols, ketones, esters, halogenated hydrocarbons, and organic solvents that destroy standard membrane materials during routine processing
• Low protein binding properties maintain biomolecule integrity throughout clarification, critical when your downstream analyses require preserving accurate protein concentrations across sample preparation steps
• Extended temperature stability to 80°C accommodates warm sample filtration and elevated-temperature solvent applications that exceed thermal limitations of conventional membrane chemistries
• 0.45µm pore size removes particulates and cellular debris from organic and pre-wetted aqueous samples, providing clarification without sterile-grade bacterial retention

Key Construction Characteristics

• Robust polypropylene housing withstands operating pressures to 72.5psi and temperatures to 80°C, delivering mechanical strength when your processing protocols challenge standard equipment
• Validated 116psi burst pressure ensures structural integrity during high-pressure filtration operations, preventing catastrophic failure when workflows demand reliable performance under stress
• Double Luer Lock connections secure both inlet and outlet ports, eliminating disconnection risks when handling aggressive solvents under pressure in critical applications
• 25mm diameter platform supports medium-volume clarification for 10-100ml samples, balancing processing capacity with material economy in your routine laboratory operations

Built to support your chemical analysis workflows where standard hydrophilic membranes fail under aggressive solvents, hydrophobic PVDF construction delivers the chemical resistance essential for reliable clarification. The 25mm platform with 116psi burst pressure and 80°C capability processes medium-volume samples consistently. Combined with double Luer Lock security and low protein binding characteristics, this configuration ensures your laboratory achieves the operational confidence required for organic solvent clarification, air venting applications, and chemically demanding sample preparation where membrane compatibility determines analytical success.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

4.35psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Polypropylene (PP)

Diameter

25mm

Dimensions (W x D x H)

21.8mmx28.6mm

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

80℃

Pack Count

100

Pore Size (µm)

0.45

Sterility

Nonsterile

Weight

0.58

Wetability

Hydrophobic

• Organic Solvent Clarification - Removes particulates from HPLC mobile phases and analytical reagents in aggressive solvents incompatible with hydrophilic membranes
• Air Venting Operations - Enables gas displacement from filtration assemblies and liquid handling systems, leveraging hydrophobic properties for specialized venting
• Chemical Sample Preparation - Clarifies samples in organic media before instrumental analysis, maintaining chemical compatibility throughout demanding preparation workflows
• HPLC Sample Processing - Protects chromatography systems from particulate fouling in organic and mixed-solvent samples, extending column life and resolution
• Protein Formulation Clarification - Filters protein solutions in organic co-solvents with minimal adsorption, preparing samples for downstream purification procedures
• Environmental Extract Analysis - Clarifies organic extracts from environmental samples before chromatographic analysis, supporting regulatory compliance protocols