Tisch
PVDF Syringe Filters, 0.22 um, 25mm, Double Luer Lock, PP Housing, Sterile, 100/Pk SKU: SPEC18212

Polyvinylidene Fluoride (PVDF) Syringe Filters - SPEC18212

Featuring hydrophobic polyvinylidene fluoride membrane technology in a sterile 25mm format, this syringe filter delivers 0.22µm absolute filtration for critical applications requiring both sterile-grade performance and exceptional chemical resistance across aggressive solvent systems. Your samples benefit from PVDF's low protein binding characteristics. This combination makes it ideal for HPLC mobile phase preparation, organic solvent filtration, and LC-MS sample processing where membrane compatibility determines analytical success.

Key PVDF Membrane Characteristics

• Hydrophobic membrane design requires initial wetting with alcohol before processing aqueous solutions, ensuring complete activation and consistent flow rates throughout your filtration process
• Exceptional chemical resistance maintains structural integrity when filtering aggressive organic solvents, strong acids, and bases that would degrade conventional membrane materials
• 0.22µm absolute pore size provides sterile-grade filtration by removing bacteria and particles, protecting your critical analytical instrumentation from contamination
• Ultra-low protein binding preserves protein concentration and activity in biological samples, preventing analyte loss that compromises quantitative accuracy
• Broad solvent compatibility handles diverse mobile phases including acetonitrile, methanol, and chlorinated solvents common in HPLC and chromatography workflows

Key Construction Characteristics

• Polypropylene housing withstands temperatures up to 80°C while maintaining chemical compatibility with your aggressive solvents and sample matrices
• Double luer lock connection creates secure, leak-proof attachment to syringes and lines, preventing disconnection during high-pressure filtration operations
• 4.9cm² filtration area processes medium sample volumes efficiently while maintaining consistent flow rates and filtration performance
• 72.5psi maximum operating pressure supports manual syringe filtration and integration with low-pressure pumping systems for automated sample preparation

When your analytical workflows demand sterile filtration across diverse solvent systems from polar aqueous buffers to nonpolar organics, membrane selection directly impacts data quality. PVDF's chemical versatility handles the complete solvent spectrum your laboratory encounters. Sterile individually-wrapped units maintain your contamination control protocols while delivering the solvent resistance and low protein binding that preserve sample integrity and protect your expensive analytical columns from particle damage.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

7.25psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Polypropylene (PP)

Diameter

25mm

Dimensions (W x D x H)

21.8mmx28.6mm

Filtration Area

4.9cm²

Material

Polyvinylidene Fluoride (PVDF)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

80℃

Pack Count

100

Pore Size (µm)

0.22

Sterility

Sterile

Weight

0.70

Wetability

Hydrophobic

• HPLC Mobile Phase Preparation — Remove particulates from mobile phases before they reach columns, extending column life and baseline stability
• LC-MS Sample Processing — Filter biological samples before mass spectrometry, protecting ionization sources while preserving analyte integrity
• Organic Solvent Filtration — Process aggressive solvents including acetonitrile and chloroform where chemical compatibility prevents degradation
• Biological Sample Clarification — Remove cellular debris from protein solutions and culture media while minimizing protein adsorption
• Final Product Sterilization — Achieve sterile filtration of heat-sensitive formulations where terminal sterilization compromises stability
• Environmental Analysis — Prepare water and soil extracts for chromatography, removing suspended solids that interfere with detection